In the past years, there has been a remarkable development of high-throughput omics (HTO)
technologies such as genomics, epigenomics, transcriptomics, proteomics and …

The laboratory rat has been used for a long time as the model of choice in several
biomedical disciplines. Numerous inbred strains have been isolated, displaying a wide …

Heterogeneous Stock (HS) rats are a genetically diverse outbred rat population that is
widely used for studying genetics of behavioral and physiological traits. Mapping …

In patients with cancer, individualized treatment strategies are generally guided by an
analysis of molecular biomarkers. However, genetic instability allows tumor cells to lose …

Metabolic syndrome is a complex disorder that comprises several other complex disorders,
including obesity, hypertension, dyslipidemia, and diabetes. There are several rat models …

Abstract Metabolic Syndrome (MetS) is a highly heritable disease and a major public health
burden worldwide. MetS diagnosis criteria is met by the simultaneous presence of any three …

Previously, we reported that cervical vagal nerve stimulation (VNS) increases blood glucose
levels and inhibits insulin secretion in anesthetized rats through afferent signaling. Since …

Biological interpretation of a large amount of gene or protein data is complex. Ontology
analysis tools are imperative in finding functional similarities through overrepresentation or …

Complementary to traditional gene mapping approaches used to identify the hereditary
components of complex diseases, integrative genomics and systems genetics have …

Banded leaf and sheath blight (BLSB) in maize is a soil-borne fungal disease caused by
Rhizoctonia solani Kühn, resulting in significant yield losses. Investigating the genes …