The role of neuroinflammation in postoperative cognitive dysfunction: moving from hypothesis to treatment
SA Safavynia, PA Goldstein - Frontiers in psychiatry, 2019 - frontiersin.org
Postoperative cognitive dysfunction (POCD) is a common complication of the surgical
experience and is common in the elderly and patients with preexisting neurocognitive …
experience and is common in the elderly and patients with preexisting neurocognitive …
Processed electroencephalogram and evoked potential techniques for amelioration of postoperative delirium and cognitive dysfunction following non‐cardiac and non …
Y Punjasawadwong, W Chau‐in… - Cochrane Database …, 2018 - cochranelibrary.com
Background Postoperative delirium (POD) and postoperative cognitive dysfunction (POCD)
may complicate a patient's postoperative recovery in several ways. Monitoring of processed …
may complicate a patient's postoperative recovery in several ways. Monitoring of processed …
[HTML][HTML] Microglia mediate postoperative hippocampal inflammation and cognitive decline in mice
X Feng, M Valdearcos, Y Uchida, D Lutrin, M Maze… - JCI insight, 2017 - ncbi.nlm.nih.gov
Surgery can induce cognitive decline, a risk that increases with advancing age. In rodents,
postoperative cognitive decline (POCD) is associated with the inflammatory activation of …
postoperative cognitive decline (POCD) is associated with the inflammatory activation of …
[HTML][HTML] Neuroinflammation-mediated mitochondrial dysregulation involved in postoperative cognitive dysfunction
Y Yang, Y Liu, J Zhu, S Song, Y Huang… - Free Radical Biology …, 2022 - Elsevier
Neuroinflammation following peripheral surgery is a pivotal pathogenic mechanism of
postoperative cognitive dysfunction (POCD). However, the key site of inflammation-mediated …
postoperative cognitive dysfunction (POCD). However, the key site of inflammation-mediated …
Does general anesthesia affect neurodevelopment in infants and children?
ME McCann, SG Soriano - Bmj, 2019 - bmj.com
General anesthesia has been unequivocally linked to abnormal development of the central
nervous system, leading to neurocognitive impairments in laboratory models. In vitro and in …
nervous system, leading to neurocognitive impairments in laboratory models. In vitro and in …
Perioperative cerebrospinal fluid and plasma inflammatory markers after orthopedic surgery
Background Postoperative delirium is prevalent in older patients and associated with worse
outcomes. Recent data in animal studies demonstrate increases in inflammatory markers in …
outcomes. Recent data in animal studies demonstrate increases in inflammatory markers in …
Research progress on the role of inflammatory mechanisms in the development of postoperative cognitive dysfunction
X Tan, LL Qiu, J Sun - BioMed research international, 2021 - Wiley Online Library
Postoperative cognitive dysfunction (POCD), as one of the common postoperative
complications, mainly occurs after surgery and anesthesia, especially in the elderly. It refers …
complications, mainly occurs after surgery and anesthesia, especially in the elderly. It refers …
Postoperative cognitive dysfunction in the aged: the collision of neuroinflammaging with perioperative neuroinflammation
AL Luo, J Yan, XL Tang, YL Zhao, BY Zhou… - Inflammopharmacology, 2019 - Springer
The aging population is burgeoning globally and this trend presents great challenges to the
current healthcare system as the growing number of aged individuals receives procedures …
current healthcare system as the growing number of aged individuals receives procedures …
Perioperative brain health in the older adult: a patient safety imperative
While people 65 years of age and older represent 16% of the population in the United
States, they account for> 40% of surgical procedures performed each year. Maintaining …
States, they account for> 40% of surgical procedures performed each year. Maintaining …
Challenges in postdischarge function and recovery: the case of fast-track hip and knee arthroplasty
EK Aasvang, IE Luna, H Kehlet - BJA: British Journal of …, 2015 - academic.oup.com
This narrative review updates the recent advances in our understanding of the multifactorial
pathogenesis for reduced postdischarge physical and cognitive function after fast-track …
pathogenesis for reduced postdischarge physical and cognitive function after fast-track …