[HTML][HTML] PIRCHE-II: an algorithm to predict indirectly recognizable HLA epitopes in solid organ transplantation
K Geneugelijk, E Spierings - Immunogenetics, 2020 - Springer
Human leukocyte antigen (HLA) mismatches between donors and recipients may lead to
alloreactivity after solid organ transplantation. Over the last few decades, our knowledge of …
alloreactivity after solid organ transplantation. Over the last few decades, our knowledge of …
Consensus guidelines on the testing and clinical management issues associated with HLA and non-HLA antibodies in transplantation
BD Tait, C Süsal, HM Gebel, PW Nickerson… - …, 2013 - journals.lww.com
Background The introduction of solid-phase immunoassay (SPI) technology for the detection
and characterization of human leukocyte antigen (HLA) antibodies in transplantation while …
and characterization of human leukocyte antigen (HLA) antibodies in transplantation while …
Predicting alloreactivity in transplantation
K Geneugelijk, KA Thus… - Journal of immunology …, 2014 - Wiley Online Library
Human leukocyte Antigen (HLA) mismatching leads to severe complications after solid‐
organ transplantation and hematopoietic stem‐cell transplantation. The alloreactive …
organ transplantation and hematopoietic stem‐cell transplantation. The alloreactive …
[HTML][HTML] Substituting imputation of HLA antigens for high-resolution HLA typing: Evaluation of a multiethnic population and implications for clinical decision making in …
RM Engen, AM Jedraszko, MA Conciatori… - American Journal of …, 2021 - Elsevier
Molecular mismatch analysis for assessment of histocompatibility in transplantation requires
high-resolution HLA typing. Algorithms to “guesstimate” high-resolution from low-resolution …
high-resolution HLA typing. Algorithms to “guesstimate” high-resolution from low-resolution …
[HTML][HTML] Identification of risk epitope mismatches associated with de novo donor-specific HLA antibody development in cardiothoracic transplantation
JA McCaughan, RK Battle, SKS Singh… - American journal of …, 2018 - Elsevier
The development of de novo donor-specific HLA antibodies (dnDSA) after transplantation is
associated with graft failure, mortality, and cost. There is no effective therapeutic intervention …
associated with graft failure, mortality, and cost. There is no effective therapeutic intervention …
The 25th anniversary of the Eurotransplant Acceptable Mismatch program for highly sensitized patients
S Heidt, MD Witvliet, GW Haasnoot, FHJ Claas - Transplant immunology, 2015 - Elsevier
Abstract In 2014, the Eurotransplant Acceptable Mismatch (AM) program celebrated its 25th
anniversary. The AM program was initiated to enhance transplantation of highly sensitized …
anniversary. The AM program was initiated to enhance transplantation of highly sensitized …
Predicting HLA class II alloantigen immunogenicity from the number and physiochemical properties of amino acid polymorphisms
V Kosmoliaptsis, LD Sharples, AN Chaudhry… - …, 2011 - journals.lww.com
Background. We have shown previously that human leukocyte antigen (HLA) class I
immunogenicity can be predicted by the number, position, and physiochemical differences …
immunogenicity can be predicted by the number, position, and physiochemical differences …
Strategic use of epitope matching to improve outcomes
C Wiebe, P Nickerson - Transplantation, 2016 - journals.lww.com
Understanding the events leading to allorecognition and the subsequent effector pathways
engaged is key for the development of strategies to prolong graft survival. Optimizing patient …
engaged is key for the development of strategies to prolong graft survival. Optimizing patient …
Antibody‐reactive epitope determination with HLAMatchmaker and its clinical applications
RJ Duquesnoy - Tissue antigens, 2011 - Wiley Online Library
Antibodies against allogeneic human leukocyte antigen (HLA) molecules are important
impediments to the success of different clinical procedures including transplantation and …
impediments to the success of different clinical procedures including transplantation and …
[HTML][HTML] Impact of donor mismatches at individual HLA-A,-B,-C,-DR, and-DQ loci on the development of HLA-specific antibodies in patients listed for repeat renal …
V Kosmoliaptsis, O Gjorgjimajkoska, LD Sharples… - Kidney international, 2014 - Elsevier
We have analyzed the relationship between donor mismatches at each HLA locus and
development of HLA locus–specific antibodies in patients listed for repeat transplantation …
development of HLA locus–specific antibodies in patients listed for repeat transplantation …