Therapeutic potential of phenolic compounds in medicinal plants—Natural health products for human health

W Sun, MH Shahrajabian - Molecules, 2023 - mdpi.com
Phenolic compounds and flavonoids are potential substitutes for bioactive agents in
pharmaceutical and medicinal sections to promote human health and prevent and cure …

Antioxidant, anti-inflammatory, anti-menopausal, and anti-cancer effects of lignans and their metabolites

WY Jang, MY Kim, JY Cho - International journal of molecular sciences, 2022 - mdpi.com
Since chronic inflammation can be seen in severe, long-lasting diseases such as cancer,
there is a high demand for effective methods to modulate inflammatory responses. Among …

A comprehensive review of flaxseed (Linum usitatissimum L.): health-affecting compounds, mechanism of toxicity, detoxification, anticancer and potential risk

A Mueed, S Shibli, M Jahangir, S Jabbar… - Critical Reviews in …, 2023 - Taylor & Francis
Flaxseed consumption (Linum usitatissimum L.) has increased due to its potential health
benefits, such as protection against inflammation, diabetes, cancer, and cardiovascular …

The renaissance of plant mucilage in health promotion and industrial applications: A review

K Dybka-Stępień, A Otlewska, P Góźdź, M Piotrowska - Nutrients, 2021 - mdpi.com
Plant mucilage is a renewable and cost-effective source of plant-based compounds that are
biologically active, biodegradable, biocompatible, nontoxic, and environmentally friendly …

The role of flaxseed in improving human health

W Nowak, M Jeziorek - Healthcare, 2023 - mdpi.com
Flaxseed contains high amounts of biologically active components such as α-linolenic acid,
lignans, and dietary fiber. Due to its numerous nutritional properties, flaxseed has been …

Impacting the remedial potential of nano delivery-based flavonoids for breast cancer treatment

RK Sindhu, R Verma, T Salgotra, MH Rahman, M Shah… - Molecules, 2021 - mdpi.com
Breast cancer persists as a diffuse source of cancer despite persistent detection and
treatment. Flavonoids, a type of polyphenol, appear to be a productive option in the …

Secoisolariciresinol diglucoside induces pyroptosis by activating caspase‐1 to cleave GSDMD in colorectal cancer cells

T Chen, Z Wang, J Zhong, L Zhang… - Drug Development …, 2022 - Wiley Online Library
Secoisolariciresinol diglucoside (SDG) is the main component of lignans with various
biological activities, including anticancer activity. However, whether SDG has obvious …

Anticancer potential of flaxseed lignans, their metabolites and synthetic counterparts in relation with molecular targets: current challenges and future perspectives

A Mueed, Z Deng, SA Korma, S Shibli, M Jahangir - Food & Function, 2023 - pubs.rsc.org
Lignans are known dietary polyphenols found in cereals, plants and seeds. Flaxseed is one
of the major sources of lignans mainly existing in the form of secoisolariciresinol diglucoside …

Pharmacological, nutraceutical, and nutritional properties of flaxseed (Linum usitatissimum): An insight into its functionality and disease mitigation

S Noreen, T Tufail, HB Ul Ain… - Food Science & …, 2023 - Wiley Online Library
Flaxseed (Linum usitatissimum L.) is derived from the flax plant, an annual herb. The primary
relevance of flaxseed is in the human nutrition sector, where it is emerging as a significant …

Secoisolariciresinol diglucoside mitigates benzo [a] pyrene-induced liver and kidney toxicity in mice via miR-101a/MKP-1-mediated p38 and ERK pathway

J Ge, R Hao, X Rong, QP Dou, X Tan, G Li, F Li… - Food and Chemical …, 2022 - Elsevier
Abstract Benzo [a] pyrene (BaP) can cause hepatorenal toxicity. Secoisolariciresinol
diglucoside (SDG), a polyphenolic compound present in flaxseed, has shown a variety of …