Metabolomic analysis in inflammatory bowel disease: a systematic review

K Gallagher, A Catesson, JL Griffin… - Journal of Crohn's …, 2021 - academic.oup.com
Abstract Background and Aims The inflammatory bowel diseases [IBD], Crohn's disease and
ulcerative colitis, are chronic, idiopathic gastrointestinal diseases. Although their precise …

Fat of the gut: epithelial phospholipids in inflammatory bowel diseases

LV Boldyreva, MV Morozova, SS Saydakova… - International journal of …, 2021 - mdpi.com
Inflammatory bowel diseases (IBD) comprise a distinct set of clinical symptoms resulting
from chronic inflammation within the gastrointestinal (GI) tract. Despite the significant …

Alterations in lipid, amino acid, and energy metabolism distinguish Crohn's disease from ulcerative colitis and control subjects by serum metabolomic profiling

EA Scoville, MM Allaman, CT Brown, AK Motley… - Metabolomics, 2018 - Springer
Introduction Biomarkers are needed in inflammatory bowel disease (IBD) to help define
disease activity and identify underlying pathogenic mechanisms. We hypothesized that …

Integrative analysis of the inflammatory bowel disease serum metabolome improves our understanding of genetic etiology and points to novel putative therapeutic …

AF Di'Narzo, SM Houten, R Kosoy, R Huang, FM Vaz… - Gastroenterology, 2022 - Elsevier
Background & Aims Polygenic and environmental factors are underlying causes of
inflammatory bowel disease (IBD). We hypothesized that integration of the genetic loci …

Integrating omics for a better understanding of inflammatory bowel disease: a step towards personalized medicine

M Kumar, M Garand, S Al Khodor - Journal of translational medicine, 2019 - Springer
Abstract Background Inflammatory Bowel Disease (IBD) is a multifactorial chronic disease.
Understanding only one aspect of IBD pathogenesis does not reflect the complex nature of …

Noni (Morinda citrifolia L.) Fruit Polysaccharides Regulated IBD Mice Via Targeting Gut Microbiota: Association of JNK/ERK/NF-κB Signaling Pathways

MY Jin, XY Wu, MY Li, XT Li, RM Huang… - Journal of Agricultural …, 2021 - ACS Publications
Inflammatory bowel disease (IBD) is a disease characterized by intestinal inflammation with
immune dysregulation and intestinal microecological imbalance. In a dextran sulfate sodium …

Modeling environmental risk factors of autism in mice induces IBD-related gut microbial dysbiosis and hyperserotonemia

JS Lim, MY Lim, Y Choi, GP Ko - Molecular brain, 2017 - Springer
Autism spectrum disorder (ASD) is a range of neurodevelopmental conditions that are
sharply increasing in prevalence worldwide. Intriguingly, ASD is often accompanied by an …

Omics and multi-omics analysis for the early identification and improved outcome of patients with psoriatic arthritis

R Gurke, A Bendes, J Bowes, M Koehm, RM Twyman… - Biomedicines, 2022 - mdpi.com
The definitive diagnosis and early treatment of many immune-mediated inflammatory
diseases (IMIDs) is hindered by variable and overlapping clinical manifestations. Psoriatic …

UPLC–QTOF-MS-based plasma lipidomic profiling reveals biomarkers for inflammatory bowel disease diagnosis

S Guan, B Jia, K Chao, X Zhu, J Tang, M Li… - Journal of proteome …, 2019 - ACS Publications
Identification of new biomarkers may help in the early diagnosis of inflammatory bowel
disease (IBD). In this study, ultrahigh-performance liquid chromatography equipped with …

Evaluation of nutritional characteristics reveals similar prevalence of malnutrition in patients with ulcerative colitis and Crohn's disease

A Singh, V Midha, R Mahajan, S Verma… - Digestive Diseases and …, 2023 - Springer
Background Inflammatory bowel disease (IBD) is associated with an increased risk of
malnutrition and sarcopenia. Aims To evaluate the nutritional status of patients with IBD and …