The drive for evidence-based decision-making has highlighted the shortcomings of
traditional orthopaedic literature. Although high-quality, prospective, randomized studies in …

With advances in the effectiveness of treatment and disease management, the contribution
of chronic comorbid diseases (comorbidities) found within the Charlson comorbidity index to …

Background—The rate of hospitalization for venous thromboembolism (VTE) is increasing in
the United States. Although predictors of hospital-acquired VTE are well-known, triggers of …

Background: Although venous thromboembolism (VTE) is a significant complication for
patients with multiple myeloma (MM) receiving immunomodulatory drugs (IMiDs), no …

Background: Although early aseptic mechanical failure after total knee arthroplasty has been
reported in younger patients, it is unknown whether early revision due to periprosthetic joint …

Patients with immune thrombocytopenia (ITP) who relapse after an initial trial of
corticosteroid treatment present a therapeutic challenge. Current guidelines recommend …

The US-wide prevalence of venous thromboembolism (VTE) is unclear, with reported VTE
incidence estimates varying widely. This retrospective analysis of healthcare claims data …

Background: Apixaban and rivaroxaban are replacing vitamin K antagonists for the
treatment of venous thromboembolism (VTE) in adults; however, head-to-head comparisons …

Deep vein thrombosis (DVT) is a blood clot that occurs in a deep vein of the body;
pulmonary embolism (PE) occurs when a clot breaks free and enters the arteries of the …

Activation of the hemostatic system occurs in patients with sickle cell disease. The extent to
which this activation contributes to sickle cell pathophysiology is uncertain. Clinical trials of …