Cellular and molecular mechanisms underlying prostate cancer development: therapeutic implications
U Testa, G Castelli, E Pelosi - Medicines, 2019 - mdpi.com
Prostate cancer is the most frequent nonskin cancer and second most common cause of
cancer-related deaths in man. Prostate cancer is a clinically heterogeneous disease with …
cancer-related deaths in man. Prostate cancer is a clinically heterogeneous disease with …
The chromodomain helicase DNA-binding chromatin remodelers: family traits that protect from and promote cancer
AA Mills - Cold Spring Harbor perspectives in …, 2017 - perspectivesinmedicine.cshlp.org
A plethora of mutations in chromatin regulators in diverse human cancers is emerging,
attesting to the pivotal role of chromatin dynamics in tumorigenesis. A recurrent theme is …
attesting to the pivotal role of chromatin dynamics in tumorigenesis. A recurrent theme is …
New developments in mechanisms of prostate cancer progression
N Howard, M Clementino, D Kim, L Wang… - Seminars in cancer …, 2019 - Elsevier
Prostate cancer is the most prevalent type of cancer in men. The etiology of prostate cancer
development and the mechanisms underlying androgen-independent progression remains …
development and the mechanisms underlying androgen-independent progression remains …
A phase II study of AT-101 to overcome Bcl-2–mediated resistance to androgen deprivation therapy in patients with newly diagnosed castration-sensitive metastatic …
MN Stein, M Hussain, WM Stadler, G Liu… - Clinical genitourinary …, 2016 - Elsevier
Background We conducted a phase II study in men with castration-sensitive metastatic
prostate cancer to test the hypothesis that AT-101, a small molecule Bcl-2 inhibitor, has …
prostate cancer to test the hypothesis that AT-101, a small molecule Bcl-2 inhibitor, has …
Mueller matrix imaging of prostate bulk tissues; Polarization parameters as a discriminating benchmark
S Badieyan, A Ameri, MR Razzaghi… - Photodiagnosis and …, 2019 - Elsevier
The polarimetry imaging technique has provided a powerful tool for discriminating normal
from cancerous tissues. In this paper, based on the backscattering Mueller matrix imaging of …
from cancerous tissues. In this paper, based on the backscattering Mueller matrix imaging of …
The roles of SNF2/SWI2 nucleosome remodeling enzymes in blood cell differentiation and leukemia
P Prasad, A Lennartsson… - BioMed Research …, 2015 - Wiley Online Library
Here, we review the role of sucrose nonfermenting (SNF2) family enzymes in blood cell
development. The SNF2 family comprises helicase‐like ATPases, originally discovered in …
development. The SNF2 family comprises helicase‐like ATPases, originally discovered in …
DNA alterations in the tumor genome and their associations with clinical outcome in prostate cancer
W Liu - Asian journal of andrology, 2016 - journals.lww.com
Although most prostate cancer (PCa) cases are not life-threatening, approximately 293 000
men worldwide die annually due to PCa. These lethal cases are thought to be caused by …
men worldwide die annually due to PCa. These lethal cases are thought to be caused by …
Frequency of PTEN alterations, TMPRSS2-ERG fusion and their association in prostate cancer
ZR Fallahabadi, MRN Daloii, R Mahdian, F Behjati… - Gene, 2016 - Elsevier
Background Phosphatase and tensin homolog (PTEN) gene aberration and trans
membrane protease, serine 2 (TMPRSS2)–v-ets avian erythroblastosis virus E26 oncogene …
membrane protease, serine 2 (TMPRSS2)–v-ets avian erythroblastosis virus E26 oncogene …
CHD1, a multifaceted epigenetic remodeler in prostate cancer
Chromatin remodeling proteins contribute to DNA replication, transcription, repair, and
recombination. The chromodomain helicase DNA-binding (CHD) family of remodelers plays …
recombination. The chromodomain helicase DNA-binding (CHD) family of remodelers plays …
Precision medicine: Implications for science and practice
S Ganesan, L Rodriguez-Rodriguez… - Journal of the American …, 2016 - journals.lww.com
As aptly stated by President John F Kennedy,“Change is the law of life. And those who look
only to the past or the present are certain to miss the future.” 1 This quote is a reminder that …
only to the past or the present are certain to miss the future.” 1 This quote is a reminder that …