Haemoglobinopathies including the thalassemias and sickle cell disease are known to be
prevalent inherited disorders in most Arab countries with varying prevalence rates and …

Studies of hemoglobin S haplotypes in African subpopulations have potential implications
for patient care and our understanding of genetic factors that have shaped the prevalence of …

Background: Sickle cell anemia (SCA) is an inherited blood disease with known
complications as a result of certain pathophysiological dysfunctions. It has been suggested …

Hemoglobinopathies are major health problems among Iraqi Kurds, who are a distinct ethnic
group inhabiting North and Northeastern Iraq. We reviewed published literature on these …

Sickle cell hemoglobin is the result of a mutation at the sixth amino acid position of the beta
(β) globin chain. The HBB* S gene is in linkage disequilibrium with five main haplotypes in …

This comprehensive review provides an insight into the pathophysiology, epidemiology,
evaluation, and treatment of sickle cell anemia (SCA)-related stroke in developed and …

ABSTRACT Introduction and Aim: Beta-thalassemia is a serious inherited genetic disorder
and an increasing health burden globally. Beta-thalassemia is caused by genetic globin …

Objective To evaluate the feasibility and effectiveness of a preventive programme for
haemoglobinopathies in a single centre in Northeastern Iraq. Methods Premarital screening …

Background: A program for the prevention of major hemoglobinopathies was initiated in
2008 in the Kurdistan region of Iraq. This study reports on the achievements and challenges …

Background: Sickle cell disease (SCD) is a monogenic, phenotypically highly variable
disease with multisystem pathology. The phenotypic heterogeneity of SCD is attributed to …