Zebrafish in toxicology and environmental health
K Bambino, J Chu - Current topics in developmental biology, 2017 - Elsevier
As manufacturing processes and development of new synthetic compounds increase to
keep pace with the expanding global demand, environmental health, and the effects of …
keep pace with the expanding global demand, environmental health, and the effects of …
Zebrafish as the toxicant screening model: Transgenic and omics approaches
The production of large amounts of synthetic industrial and biomedical compounds, together
with environmental pollutants, poses a risk to our ecosystem and induces negative effects on …
with environmental pollutants, poses a risk to our ecosystem and induces negative effects on …
Graphene oxide elicits microbiome-dependent type 2 immune responses via the aryl hydrocarbon receptor
The gut microbiome produces metabolites that interact with the aryl hydrocarbon receptor
(AhR), a key regulator of immune homoeostasis in the gut,. Here we show that oral exposure …
(AhR), a key regulator of immune homoeostasis in the gut,. Here we show that oral exposure …
Comparative developmental toxicity of a comprehensive suite of polycyclic aromatic hydrocarbons
MC Geier, AC Chlebowski, L Truong… - Archives of …, 2018 - Springer
Polycyclic aromatic hydrocarbons (PAHs) are widespread environmental contaminants that
occur in complex mixtures. Several PAHs are known or suspected mutagens and/or …
occur in complex mixtures. Several PAHs are known or suspected mutagens and/or …
Cytochrome P450-dependent biotransformation capacities in embryonic, juvenile and adult stages of zebrafish (Danio rerio)—a state-of-the-art review
AK Loerracher, T Braunbeck - Archives of Toxicology, 2021 - Springer
Given the strong trend to implement zebrafish (Danio rerio) embryos as translational model
not only in ecotoxicological, but also toxicological testing strategies, there is an increasing …
not only in ecotoxicological, but also toxicological testing strategies, there is an increasing …
Zebrafish: A marvel of high-throughput biology for 21st century toxicology
The evolutionary conservation of genomic, biochemical, and developmental features
between zebrafish and humans is gradually coming into focus, with the end result that the …
between zebrafish and humans is gradually coming into focus, with the end result that the …
AhR agonist activity confirmation of polyhalogenated carbazoles (PHCZs) using an integration of in vitro, in vivo, and in silico models
Polyhalogenated carbazoles (PHCZs) are a kind of rising environmental pollutant that has
been reported to pose high risk to human beings and the natural environment. PHCZs are of …
been reported to pose high risk to human beings and the natural environment. PHCZs are of …
A review of the functional roles of the zebrafish aryl hydrocarbon receptors
Over the last 2 decades, the zebrafish (Danio rerio) has emerged as a stellar model for
unraveling molecular signaling events mediated by the aryl hydrocarbon receptor (AHR), an …
unraveling molecular signaling events mediated by the aryl hydrocarbon receptor (AHR), an …
[HTML][HTML] Non-additive mixture effects of benzo [a] pyrene and pesticides in vitro and in vivo: Role of AhR signaling
Polycyclic aromatic hydrocarbons (PAHs) and pesticides are two major groups of
environmental contaminants which humans are simultaneously exposed to. However …
environmental contaminants which humans are simultaneously exposed to. However …
Graphene oxide nanosheets induce DNA damage and activate the base excision repair (BER) signaling pathway both in vitro and in vivo
CJ Lu, XF Jiang, M Junaid, YB Ma, PP Jia, HB Wang… - Chemosphere, 2017 - Elsevier
Graphene oxide (GO) has widespread concerns in the fields of biological sciences and
medical applications. Currently, studies have reported that excessive GO exposure can …
medical applications. Currently, studies have reported that excessive GO exposure can …