Abstract Withania somnifera (L.) Dunal (Solanaceae) has been used as a traditional
Rasayana herb for a long time. Traditional uses of this plant indicate its ameliorative …

Oxidative stress including DNA damage, increased lipid and protein oxidation, are important
features of aging and neurodegeneration suggesting that endogenous antioxidant protective …

Parkinson's disease (PD) is a neurodegenerative disorder characterized by a preferential
loss of the dopaminergic neurons of the substantia nigrapars compacta. Although the …

Neurological disorders in humans can be modeled in animals using standardized
procedures that recreate specific pathogenic events and their behavioral outcomes. The …

Animal models are important tools in experimental medical science to better understand
pathogenesis of human diseases. Once developed, these models can be exploited to test …

Gallic acid and its derivatives are a group of naturally occurring polyphenol antioxidants
which have recently been shown to have potential healthy effects. In order to understand the …

Cannabinoids have been reported to provide neuroprotection in acute and chronic
neurodegeneration. In this study, we examined whether they are also effective against the …

Animal models are an important aid in experimental medical science because they enable
one to study the pathogenetic mechanisms and the therapeutic principles of treating the …

6‐Hydroxydopamine (6‐OHDA) is a dopaminergic neurotoxin putatively involved in the
pathogenesis of Parkinson's disease (PD). Its neurotoxicity has been related to the …

6-Hydroxydopamine (6-OHDA) is one of the most widely used rat models for Parkinson's
disease. There is ample evidence in the literature that 6-OHDA elicits its toxic manifestations …