Brain-based mechanisms of late-life depression: implications for novel interventions

FM Gunning, LE Oberlin, M Schier… - Seminars in cell & …, 2021 - Elsevier
Late-life depression (LLD) is a particularly debilitating illness. Older adults suffering from
depression commonly experience poor outcomes in response to antidepressant treatments …

Transdiagnostic role of glutamate and white matter damage in neuropsychiatric disorders: A Systematic Review

I Luttenbacher, A Phillips, R Kazemi… - Journal of Psychiatric …, 2022 - Elsevier
Neuropsychiatric disorders including generalized anxiety disorder (GAD), obsessive-
compulsive disorder (OCD), major depressive disorder (MDD), bipolar disorder (BD), and …

Development and evaluation of a multimodal marker of major depressive disorder

J Yang, M Zhang, H Ahn, Q Zhang, TB Jin… - Human brain …, 2018 - Wiley Online Library
This study aimed to identify biomarkers of major depressive disorder (MDD), by relating
neuroimage‐derived measures to binary (MDD/control), ordinal (severe MDD/mild …

White matter abnormalities and cognitive function in euthymic patients with bipolar disorder and major depressive disorder

Y Masuda, G Okada, M Takamura… - Brain and …, 2020 - Wiley Online Library
Objectives In recent years, a growing number of diffusion tensor imaging (DTI) studies have
compared white matter integrity between patients with major depressive disorder (MDD) and …

[HTML][HTML] Neural mechanisms underlying cognitive impairment in depression and cognitive benefits of exercise intervention

H Tian, Z Wang, Y Meng, L Geng, H Lian, Z Shi… - Behavioural Brain …, 2025 - Elsevier
Depression is associated with functional brain impairments, although comprehensive
studies remain limited. This study reviews neural mechanisms underlying cognitive …

Interplay between pro-inflammatory cytokines, childhood trauma, and executive function in depressed adolescents

AT Peters, X Ren, KL Bessette, BI Goldstein… - Journal of psychiatric …, 2019 - Elsevier
Background Pro-inflammatory cytokines have been linked to depression, early childhood
trauma, and impairment in executive function in adults. Whether these links are present …

Processing speed and sustained attention in bipolar disorder and major depressive disorder: A systematic review and meta‐analysis

B Little, M Anwyll, L Norsworthy, L Corbett… - Bipolar …, 2024 - Wiley Online Library
Objectives Cognitive impairment is a core feature of bipolar disorder (BD) and major
depressive disorder (MDD). Deficits in processing speed (PS) and sustained attention (SA) …

Investigation into local white matter abnormality in emotional processing and sensorimotor areas using an automatically annotated fiber clustering in major depressive …

Y Wu, F Zhang, N Makris, Y Ning, I Norton, S She… - NeuroImage, 2018 - Elsevier
This work presents an automatically annotated fiber cluster (AAFC) method to enable
identification of anatomically meaningful white matter structures from the whole brain …

Disrupted structural brain network organization behind depressive symptoms in major depressive disorder

J Liu, X Xu, C Zhu, L Luo, Q Wang, B Xiao… - Frontiers in …, 2020 - frontiersin.org
Major depressive disorder (MDD) is a severe and devastating condition. However, the
anatomical basis behind the affective symptoms, cognitive symptoms, and somatic …

Abnormal brain white matter in patients with right trigeminal neuralgia: a diffusion tensor imaging study

J Liu, J Zhu, F Yuan, X Zhang, Q Zhang - The journal of headache and …, 2018 - Springer
Background Idiopathic or classical trigeminal neuralgia (TN) is a chronic painful condition
characterized by intermittent pain attacks. Enough evidence demonstrates classical TN is …