Biological and functional multimorbidity—from mechanisms to management

C Langenberg, AD Hingorani, CJM Whitty - Nature Medicine, 2023 - nature.com
Globally, the number of people with multiple co-occurring diseases will increase
substantially over the coming decades, with important consequences for patients, carers …

[HTML][HTML] The global burden of multiple chronic conditions: a narrative review

C Hajat, E Stein - Preventive medicine reports, 2018 - Elsevier
Globally, approximately one in three of all adults suffer from multiple chronic conditions
(MCCs). This review provides a comprehensive overview of the resulting epidemiological …

Clinical characteristics of older patients infected with COVID-19: A descriptive study

S Niu, S Tian, J Lou, X Kang, L Zhang, H Lian… - Archives of gerontology …, 2020 - Elsevier
Objectives Since the outbreak of 2019 novel coronavirus (COVID-19), which has spread in
the world rapidly. Population have a susceptibility to COVID-19, older people were more …

Examining variation in the measurement of multimorbidity in research: a systematic review of 566 studies

ISS Ho, A Azcoaga-Lorenzo, A Akbari… - The Lancet Public …, 2021 - thelancet.com
Background A systematic understanding of how multimorbidity has been constructed and
measured is unavailable. This review aimed to examine the definition and measurement of …

Multimorbidity and quality of life: systematic literature review and meta-analysis

TT Makovski, S Schmitz, MP Zeegers, S Stranges… - Ageing research …, 2019 - Elsevier
Multimorbidity is typically defined as the co-existence of two or more chronic diseases within
an individual. Its prevalence is highest among the elderly, with poor quality of life (QoL) …

Impact of multimorbidity on healthcare costs and utilisation: a systematic review of the UK literature

M Soley-Bori, M Ashworth, A Bisquera, H Dodhia… - British Journal of …, 2021 - bjgp.org
Background Managing multimorbidity is complex for both patients and healthcare systems.
Patients with multimorbidity often use a variety of primary and secondary care services …

[HTML][HTML] Association of sleep duration at age 50, 60, and 70 years with risk of multimorbidity in the UK: 25-year follow-up of the Whitehall II cohort study

S Sabia, A Dugravot, D Léger, CB Hassen… - PLoS …, 2022 - journals.plos.org
Background Sleep duration has been shown to be associated with individual chronic
diseases but its association with multimorbidity, common in older adults, remains poorly …

Association of late-life depression with cognitive impairment: evidence from a cross-sectional study among older adults in India

T Muhammad, T Meher - BMC geriatrics, 2021 - Springer
Background Late-life depression (LLD) is considered as a prodrome to dementia and plays
a major role in the development of long-term cognitive disabilities. We aimed to estimate the …

Multimorbidity and functional impairment–bidirectional interplay, synergistic effects and common pathways

A Calderón‐Larrañaga, DL Vetrano… - Journal of internal …, 2019 - Wiley Online Library
This review discusses the interplay between multimorbidity (ie co‐occurrence of more than
one chronic health condition in an individual) and functional impairment (ie limitations in …

Securing a sustainable and fit-for-purpose UK health and care workforce

M Anderson, C O'Neill, JM Clark, A Street, M Woods… - The Lancet, 2021 - thelancet.com
Approximately 13% of the total UK workforce is employed in the health and care sector.
Despite substantial workforce planning efforts, the effectiveness of this planning has been …