Herbal medicine: biomolecular and clinical aspects

IFF Benzie, S Wachtel-Galor - 2011 - books.google.com
Responding to the increased popularity of herbal medicines and other forms of
complementary or alternative medicine world-wide, this reference reviews and evaluates …

Tunneling nanotubes and gap junctions–their role in long-range intercellular communication during development, health, and disease conditions

J Ariazi, A Benowitz, V De Biasi… - Frontiers in molecular …, 2017 - frontiersin.org
Cell-to-cell communication is essential for the organization, coordination, and development
of cellular networks and multi-cellular systems. Intercellular communication is mediated by …

Severe reactive astrocytes precipitate pathological hallmarks of Alzheimer's disease via H2O2 production

H Chun, H Im, YJ Kang, Y Kim, JH Shin, W Won… - Nature …, 2020 - nature.com
Although the pathological contributions of reactive astrocytes have been implicated in
Alzheimer's disease (AD), their in vivo functions remain elusive due to the lack of …

Tunneling nanotubes provide a route for SARS-CoV-2 spreading

A Pepe, S Pietropaoli, M Vos, G Barba-Spaeth… - Science …, 2022 - science.org
Neurological manifestations of severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) infection represent a major issue in long coronavirus disease. How SARS-CoV-2 …

Transfer of mitochondria via tunneling nanotubes rescues apoptotic PC12 cells

X Wang, HH Gerdes - Cell Death & Differentiation, 2015 - nature.com
Tunneling nanotubes (TNTs) are F-actin-based membrane tubes that form between cells in
culture and in tissues. They mediate intercellular communication ranging from electrical …

Dynamic assembly of DNA-ceria nanocomplex in living cells generates artificial peroxisome

C Yao, Y Xu, J Tang, P Hu, H Qi, D Yang - Nature Communications, 2022 - nature.com
Intracellular accumulation of reactive oxygen species (ROS) leads to oxidative stress, which
is closely associated with many diseases. Introducing artificial organelles to ROS …

Human astrocytes transfer aggregated alpha-synuclein via tunneling nanotubes

J Rostami, S Holmqvist, V Lindström… - Journal of …, 2017 - Soc Neuroscience
Many lines of evidence suggest that the Parkinson's disease (PD)-related protein α-
synuclein (α-SYN) can propagate from cell to cell in a prion-like manner. However, the …

Peering into tunneling nanotubes—The path forward

D Cordero Cervantes, C Zurzolo - The EMBO journal, 2021 - embopress.org
Abstract The identification of Tunneling Nanotubes (TNTs) and TNT‐like structures signified
a critical turning point in the field of cell‐cell communication. With hypothesized roles in …

Oxidative stress and neurotoxicity

LM Sayre, G Perry, MA Smith - Chemical research in toxicology, 2008 - ACS Publications
There is increasing awareness of the ubiquitous role of oxidative stress in
neurodegenerative disease states. A continuing challenge is to be able to distinguish …

Role of connexin 43 in different forms of intercellular communication–gap junctions, extracellular vesicles and tunnelling nanotubes

TM Ribeiro-Rodrigues… - Journal of cell …, 2017 - journals.biologists.com
Communication is important to ensure the correct and efficient flow of information, which is
required to sustain active social networks. A fine-tuned communication between cells is vital …