Simple Summary Vimentin is an important filamentous protein providing structural and
functional support to the cell. During initial stages of cancer development, vimentin …

Epithelial–mesenchymal transition (EMT) is a complex molecular program that regulates
changes in cell morphology and function during embryogenesis and tissue development …

Fibroblast growth factor (FGF) signaling pathways are essential regulators of vertebrate
skeletal development. FGF signaling regulates development of the limb bud and formation of …

Transforming growth factor-beta (TGF-β) plays multiple homeostatic roles in the regulation of
inflammation, proliferation, differentiation and would healing of various tissues. Many studies …

Autosomal dominant mutations in fibroblast growth factor receptor 3 (FGFR3) cause
achondroplasia (Ach), the most common form of dwarfism in humans, and related …

The WNT/β-catenin signalling implies its significance in maintaining an epithelial cell
phenotype, proper cell–cell junctions, and tissue homeostasis. Dysregulation of the …

Epithelial–mesenchymal transition or EMT is an extremely dynamic process involved in
conversion of epithelial cells into mesenchymal cells, stimulated by an ensemble of …

Epithelial–mesenchymal transition (EMT) is a reversible cellular process, characterized by
changes in gene expression and activation of proteins, favoring the trans-differentiation of …

Background The distant metastasis of cancer cells is a risk factor for tumor lethality and poor
prognosis in non-small-cell lung carcinoma (NSCLC). Increased SOX9 expression has been …

Metastasis and recurrence are the leading cause of mortality due to breast cancer, but the
underlying mechanisms are still poorly understood. Understanding the breast cancer …