Management of recurrent and metastatic oral cavity cancer: Raising the bar a step higher

P Szturz, JB Vermorken - Oral oncology, 2020 - Elsevier
In recurrent and/or metastatic squamous cell carcinoma of the head and neck (R/M-
SCCHN), the armamentarium of systemic anti-cancer modalities continues to grow in …

Review of outcomes after salvage surgery for recurrent squamous cell carcinoma of the head and neck

DM Hartl, J Guerlain, P Gorphe, M Kapre… - Cancers, 2023 - mdpi.com
Simple Summary Local recurrences, isolated regional recurrences, and loco-regional
recurrences are frequent after treatment for advanced stage head and neck squamous cell …

Follow-up of head and neck cancer survivors: tipping the balance of intensity

P Szturz, C Van Laer, C Simon, D Van Gestel… - Frontiers in …, 2020 - frontiersin.org
The traditional concept of post-treatment surveillance in head and neck cancer patients
relies on examinations directed at early detection of disease recurrence and/or second …

Salvage surgery for recurrent squamous cell carcinoma of the head and neck: Systematic review and meta‐analysis

MG Bulbul, TJ Genovese, K Hagan, S Rege… - Head & …, 2022 - Wiley Online Library
The present study aims to estimate a pooled hazard ratio (HR) comparing overall survival
(OS) for salvage surgery compared to nonsurgical management of recurrent head and neck …

A New Proposal for Adequate Resection Margins in Larynx and Hypopharynx Tumor Surgery—Are the RCP Guidelines Feasible?

SE Bernard, CGF van Lanschot, JA Hardillo… - Cancers, 2024 - mdpi.com
Simple Summary A total laryngectomy and/or pharyngectomy is an important therapy
modality for advanced primary and recurrent laryngeal and hypopharyngeal squamous cell …

Overall Neutrophil-to-Lymphocyte Ratio and SUVmax of Nodal Metastases Predict Outcome in Head and Neck Cancer Before Chemoradiation

J Werner, K Strobel, D Lehnick, GP Rajan - Frontiers in Oncology, 2021 - frontiersin.org
Introduction This study investigates the pretherapeutic neutrophil-to-lymphocyte ratio (NLR)
with markers of tumor metabolism in 18-fluorodeoxyglucose positron emission …

Radiosensitizing effects of curcumin alone or combined with GLUT1 siRNA on laryngeal carcinoma cells through AMPK pathway‐induced autophagy

LB Dai, JT Zhong, LF Shen, SH Zhou… - Journal of Cellular …, 2021 - Wiley Online Library
In this study, we investigated the ability of curcumin alone or in combination with GLUT1
siRNA to radiosensitize laryngeal carcinoma (LC) through the induction of autophagy …

Prior chemoradiotherapy and pathological perineural invasion predict the survival outcomes of salvage surgery in head and neck squamous cell carcinoma

NR Akali, R Buggaveeti, SV Sukumaran… - Head & …, 2021 - Wiley Online Library
Background The purpose of the study was to evaluate the oncological outcomes of salvage
surgery in squamous cell carcinoma of the head and neck (SCCHN). Methods This is a …

A pre-operative prognostic score for the selection of patients for salvage surgery after recurrent head and neck squamous cell carcinomas

V Lupato, J Polesel, FB La Torre, G Fanetti, E Fratta… - Scientific Reports, 2021 - nature.com
Salvage surgery in recurrent head and neck squamous cell carcinoma has a poor outcome,
both in terms of survival and quality of life. Therefore, the identification of pre-operative …

Patterns of failure after salvage head and neck surgery

KJ Contrera, CR Mahomva, BK Sharma, W Wei… - Oral Oncology, 2024 - Elsevier
Background Advancements in immunotherapy for recurrent head and neck cancer have
necessitated a better understanding of salvage surgical outcomes. This study aimed to …