Gliomas are the most common primary brain tumors in adults and, despite advances in the
understandings of glioma pathogenesis in the genetic era, they are still ineradicable …

The blood–brain barrier minimizes the entry of molecules into brain tissue. This restriction
arises by the presence of tight junctions (zonulae occludens) between adjacent endothelial …

Aims: Hyperglycaemia (HG), in stroke patients, is associated with worse neurological
outcome by compromising endothelial cell function and the blood–brain barrier (BBB) …

Background and Purpose—Although the incidence of type II diabetes is increasing, very little
is known regarding vascular responses in the cerebral circulation in this disease. The goals …

Endothelial-mediated dilations to selective P2Y1 and P2Y2 purinoceptor agonists [2-
methylthioadenosine triphosphate (2MeS-ATP) and uridine 5′-triphosphate (UTP) …

Introduction In this study, we aimed to target two molecules, transforming growth factor-beta
(TGF-β) and dynamin to explore their roles in blood–brain barrier (BBB) disruption in …

Volume transmission in the brain is mediated by the diffusion of neurotransmitters,
modulators and other neuroactive substances in the extracellular space. The effects of nitric …

Objective: Previous data showed that in the nucleus tractus solitarius (NTS), 5-HT3 receptors
are critically involved in the inhibition of cardiac baroreceptor reflex response occurring …

The influence of the calcium channel blocker nifedipine plus bicuculline-induced seizures
on the permeability of the blood-brain barrier to protein was studied in rats. Evans-blue was …

Despite the generally restrictive nature of the blood-brain barrier, circulating lymphocytes
can infiltrate into the central nervous system (CNS) during a variety of disease states …