Cadherins are a group of membrane proteins responsible for cell adhesion. They are crucial
for cell sorting and recognition during the morphogenesis, but they also play many other …

CDH2 belongs to the classic cadherin family of Ca2+-dependent cell adhesion molecules
with a meticulously described dual role in cell adhesion and β-catenin signaling. During …

The dosage of X-linked genes is accurately regulated with the development of fetal germ
cells (FGCs),. How aberrant dosage of X-linked genes impairs FGC development in humans …

The ovary is a female reproductive organ that plays a key role in fertility and the
maintenance of endocrine homeostasis, which is of great importance to women's health. It is …

The formation of primordial follicles occurs when germ cell nests break apart and individual
oocytes become surrounded by pregranulosa cells. Why mammalian germ cells develop in …

Spermatogonial stem cell (SSC) technologies that are currently under clinical development
to reverse human infertility hold the potential to be adapted and applied for the conservation …

Introduction: Unhealthy lifestyle choices such as alcohol, chemicals, and heat stress can
worsen male infertility. Heat stress can cause damage to the essential structure known as …

Cadherins (CDH) are crucial intercellular adhesion molecules, contributing to
morphogenesis and creating tissue barriers by regulating cells' movement, clustering and …

Methoxychlor (MXC) is a man-made organochlorine insecticide capable of disrupting
endocrine functions due to its mixed steroidal properties (estrogenic, anti-estrogenic and/or …

Biochemical signaling arising from mechanical force-induced physical changes in biological
macromolecules is a critical determinant of key physiological processes across all biological …