Understanding the relationship between brain and behavior is the fundamental challenge in
neuroscience. We focus on chemosensation and chemosensory learning in larval …

Locomotion is a complex motor behavior that may be expressed in different ways using a
variety of strategies depending upon species and pathological or environmental conditions …

Huntington's disease is an autosomal dominant neurodegenerative disorder caused by
expansion of a polyglutamine tract in the huntingtin protein that results in intracellular …

The generation of coordinated body movements relies on sensory feedback from
mechanosensitive proprioceptors. We have found that the proper function of NompC, a …

Understanding rhythmic behavior at the developmental and genetic levels has important
implications for neurobiology, medicine, evolution, and robotics. We studied rhythmic …

Drosophila larval crawling is a simple behavior that allows us to dissect the functions of
specific neurons in the intact animal and explore the roles of genes in the specification of …

Biogenic amines are believed to play important roles in producing behaviors. Although
some biogenic amines have been extensively studied in both vertebrates and invertebrates …

Abstract Drosophila Crumbs (Crb) is required for apical–basal polarity and is an apical
determinant in embryonic epithelia,. Here, we describe properties of Crb that control the …

Coordination of rhythmic locomotion depends upon a precisely balanced interplay between
central and peripheral control mechanisms [1]. Although poorly understood, peripheral …

The genetic analysis of larval neuromuscular junctions (NMJs) of Drosophila has provided
detailed insights into molecular mechanisms that control the morphological and …