[HTML][HTML] A novel strategy to characterize the pattern of β-lactam antibiotic-induced drug resistance in Acinetobacter baumannii

T Hillyer, BM Benin, C Sun, N Aguirre, B Willard… - Scientific reports, 2023 - nature.com
Abstract Carbapenem-resistant Acinetobacter baumannii (CRAb) is an urgent public health
threat, according to the CDC. This pathogen has few treatment options and causes severe …

[HTML][HTML] The integration of proteomics and metabolomics data paving the way for a better understanding of the mechanisms underlying microbial acquired drug …

S Fortuin, NC Soares - Frontiers in Medicine, 2022 - frontiersin.org
Due to an increase in the overuse of antimicrobials and accelerated incidence of drug
resistant pathogens, antimicrobial resistance has become a global health threat. In …

Proteomic interrogation of antibiotic resistance and persistence in Escherichia coli – progress and potential for medical research

D Zhang, Y Hu, Q Zhu, J Huang… - Expert Review of …, 2020 - Taylor & Francis
Introduction Escherichia coli strains possess two survival strategies to endure lethal
antibiotic exposure including antibiotic resistance and persistence, in which persistence can …

Relationship between L-lactate dehydrogenase and multidrug resistance in Staphylococcus xylosus

Z Yuan, J Wang, R Che, BO God'spower, Y Zhou… - Archives of …, 2022 - Springer
Staphylococcus xylosus is a gram-positive bacterium that has attracted much attention due
to its increasing clinical appearance, frequently associated with serious multidrug resistance …

Comparative Proteomic Analysis Reveals Antibacterial Mechanism of Patrinia scabiosaefolia Against Methicillin Resistant Staphylococcus epidermidis

X Liu, L An, S Ren, Y Zhou, W Peng - Infection and drug resistance, 2022 - Taylor & Francis
Purpose As a kind of opportunist pathogen, Staphylococcus epidermidis (MRSE) can cause
nosocomial infections and easily evolve into resistant bacteria. Among these, methicillin …

Structural–functional diversity of malaria parasite's PfHSP70-1 and PfHSP40 chaperone pair gives an edge over human orthologs in chaperone-assisted protein …

M Anas, A Shukla, A Tripathi, V Kumari… - Biochemical …, 2020 - portlandpress.com
Plasmodium falciparum, the human malaria parasite harbors a metastable proteome which
is vulnerable to proteotoxic stress conditions encountered during its lifecycle. How parasite's …

[HTML][HTML] Proteomics and metabolomics analysis reveal potential mechanism of extended-spectrum β-lactamase production in Escherichia coli

H Ma, B Lai, Y Jin, C Tian, J Liu, K Wang - RSC advances, 2020 - pubs.rsc.org
In this study, ten clinical susceptible strains and ten clinical ESBL-EC (extended-spectrum β-
lactamase-producing Escherichia coli) were screened and obtained by microbial …

Integrative proteomics and metabolomics approach to elucidate the antimicrobial effect of simvastatin on Escherichia coli

E Kocak, E Nemutlu, S Kır… - Biomedical …, 2021 - Wiley Online Library
Globally, simvastatin is one of the most commonly used statin drugs. Its antimicrobial
properties have been investigated against various pathogens. However, its effect on …

[HTML][HTML] Insights Into the Effect of Rice Stripe Virus P2 on Rice Defense by Comparative Proteomic Analysis

Z Yang, H Zhang, X Tan, Z Wei, C Wen, Z Sun… - Frontiers in …, 2022 - frontiersin.org
Rice stripe virus (RSV) has a serious effect on rice production. Our previous research had
shown that RSV P2 plays important roles in RSV infection, so in order to further understand …

[HTML][HTML] Mycobacterium avium subsp. paratuberculosis Proteome Changes Profoundly in Milk

KJH Kleinwort, BF Hobmaier, R Mayer, C Hölzel… - Metabolites, 2021 - mdpi.com
Mycobacterium avium subspecies paratuberculosis (MAP) are detectable viable in milk and
other dairy products. The molecular mechanisms allowing the adaptation of MAP in these …