Edema, hyperalgesia and myonecrosis induced by Brazilian bothropic venoms: Overview of the last decade

CCN Mamede, BB de Sousa Simamoto… - Toxicon, 2020 - Elsevier
Snakebite accidents are considered serious public health problems. They are often
neglected, and individuals who have received insufficient treatment are subjected to various …

Trends in snakebite envenomation therapy: scientific, technological and public health considerations

JM Gutierrez, B Lomonte, G León… - Current …, 2007 - ingentaconnect.com
The therapy of snakebite envenomation has been based on the parenteral administration of
animal-derived antivenoms. Despite the success of this treatment at reducing the impact of …

[图书][B] Handbook of venoms and toxins of reptiles

SP Mackessy - 2016 - taylorfrancis.com
The Handbook of Venoms and Toxins of Reptiles offers" one-stop shopping" to all biologists,
biochemists, toxicologists, physicians, clinicians, and epidemiologists, and informed …

Inflammation induced by platelet-activating viperid snake venoms: perspectives on thromboinflammation

C Teixeira, CM Fernandes, E Leiguez… - Frontiers in …, 2019 - frontiersin.org
Envenomation by viperid snakes is characterized by systemic thrombotic syndrome and
prominent local inflammation. To date, the mechanisms underlying inflammation and blood …

Importance of snake venom metalloproteinases in cell biology: effects on platelets, inflammatory and endothelial cells

AM Moura-da-Silva, D Butera… - Current pharmaceutical …, 2007 - ingentaconnect.com
Snake venom metalloproteinases (SVMPs) are widely distributed in snake venoms and play
important roles in hemostatic disorders and local tissue damage that follows snakebite. The …

Increments in cytokines and matrix metalloproteinases in skeletal muscle after injection of tissue‐damaging toxins from the venom of the snake Bothrops asper

A Rucavado, T Escalante, CFP Teixeira… - Mediators of …, 2002 - Wiley Online Library
Envenomations by the snake Bothrops asper are characterized by prominent local tissue
damage (ie myonecrosis), blistering, hemorrhage and edema. Various phospholipases A2 …

Inflammatory effects of snake venom metalloproteinases

CFP Teixeira, CM Fernandes, JP Zuliani… - Memórias do Instituto …, 2005 - SciELO Brasil
Metalloproteinases are abundant enzymes in crotaline and viperine snake venoms. They
are relevant in the pathophysiology of envenomation, being responsible for local and …

Functional variability of snake venom metalloproteinases: adaptive advantages in targeting different prey and implications for human envenomation

JL Bernardoni, LF Sousa, LS Wermelinger, AS Lopes… - PLoS …, 2014 - journals.plos.org
Snake venom metalloproteinases (SVMPs) are major components in most viperid venoms
that induce disturbances in the hemostatic system and tissues of animals envenomated by …

[HTML][HTML] Contribution of metalloproteases, serine proteases and phospholipases A2 to the inflammatory reaction induced by Bothrops jararaca crude venom in mice

BC Zychar, CS Dale, DS Demarchi, LRC Gonçalves - Toxicon, 2010 - Elsevier
Various toxins isolated from Bothrops snake venoms induce inflammatory reactions and
have been claimed to contribute to the severity of local symptoms present in this …

Jararhagin, a snake venom metalloproteinase, induces a specialized form of apoptosis (anoikis) selective to endothelial cells

I Tanjoni, R Weinlich, MS Della-Casa, PB Clissa… - Apoptosis, 2005 - Springer
Jararhagin is a snake venom metalloproteinase (SVMP) from Bothrops jararaca involved in
several hemostatic and inflammatory disorders that occur in human envenomings. In this …