Edema, hyperalgesia and myonecrosis induced by Brazilian bothropic venoms: Overview of the last decade
CCN Mamede, BB de Sousa Simamoto… - Toxicon, 2020 - Elsevier
Snakebite accidents are considered serious public health problems. They are often
neglected, and individuals who have received insufficient treatment are subjected to various …
neglected, and individuals who have received insufficient treatment are subjected to various …
Trends in snakebite envenomation therapy: scientific, technological and public health considerations
The therapy of snakebite envenomation has been based on the parenteral administration of
animal-derived antivenoms. Despite the success of this treatment at reducing the impact of …
animal-derived antivenoms. Despite the success of this treatment at reducing the impact of …
[图书][B] Handbook of venoms and toxins of reptiles
SP Mackessy - 2016 - taylorfrancis.com
The Handbook of Venoms and Toxins of Reptiles offers" one-stop shopping" to all biologists,
biochemists, toxicologists, physicians, clinicians, and epidemiologists, and informed …
biochemists, toxicologists, physicians, clinicians, and epidemiologists, and informed …
Inflammation induced by platelet-activating viperid snake venoms: perspectives on thromboinflammation
C Teixeira, CM Fernandes, E Leiguez… - Frontiers in …, 2019 - frontiersin.org
Envenomation by viperid snakes is characterized by systemic thrombotic syndrome and
prominent local inflammation. To date, the mechanisms underlying inflammation and blood …
prominent local inflammation. To date, the mechanisms underlying inflammation and blood …
Importance of snake venom metalloproteinases in cell biology: effects on platelets, inflammatory and endothelial cells
AM Moura-da-Silva, D Butera… - Current pharmaceutical …, 2007 - ingentaconnect.com
Snake venom metalloproteinases (SVMPs) are widely distributed in snake venoms and play
important roles in hemostatic disorders and local tissue damage that follows snakebite. The …
important roles in hemostatic disorders and local tissue damage that follows snakebite. The …
Increments in cytokines and matrix metalloproteinases in skeletal muscle after injection of tissue‐damaging toxins from the venom of the snake Bothrops asper
Envenomations by the snake Bothrops asper are characterized by prominent local tissue
damage (ie myonecrosis), blistering, hemorrhage and edema. Various phospholipases A2 …
damage (ie myonecrosis), blistering, hemorrhage and edema. Various phospholipases A2 …
Inflammatory effects of snake venom metalloproteinases
Metalloproteinases are abundant enzymes in crotaline and viperine snake venoms. They
are relevant in the pathophysiology of envenomation, being responsible for local and …
are relevant in the pathophysiology of envenomation, being responsible for local and …
Functional variability of snake venom metalloproteinases: adaptive advantages in targeting different prey and implications for human envenomation
JL Bernardoni, LF Sousa, LS Wermelinger, AS Lopes… - PLoS …, 2014 - journals.plos.org
Snake venom metalloproteinases (SVMPs) are major components in most viperid venoms
that induce disturbances in the hemostatic system and tissues of animals envenomated by …
that induce disturbances in the hemostatic system and tissues of animals envenomated by …
[HTML][HTML] Contribution of metalloproteases, serine proteases and phospholipases A2 to the inflammatory reaction induced by Bothrops jararaca crude venom in mice
BC Zychar, CS Dale, DS Demarchi, LRC Gonçalves - Toxicon, 2010 - Elsevier
Various toxins isolated from Bothrops snake venoms induce inflammatory reactions and
have been claimed to contribute to the severity of local symptoms present in this …
have been claimed to contribute to the severity of local symptoms present in this …
Jararhagin, a snake venom metalloproteinase, induces a specialized form of apoptosis (anoikis) selective to endothelial cells
I Tanjoni, R Weinlich, MS Della-Casa, PB Clissa… - Apoptosis, 2005 - Springer
Jararhagin is a snake venom metalloproteinase (SVMP) from Bothrops jararaca involved in
several hemostatic and inflammatory disorders that occur in human envenomings. In this …
several hemostatic and inflammatory disorders that occur in human envenomings. In this …