Alzheimer's disease (AD) is a major cause of dementia in the elderly. Pathologically, AD is
characterized by the accumulation of insoluble aggregates of Aβ-peptides that are …

Alzheimer's disease (AD) is an age-related progressive neurodegenerative disease
affecting thousands of people in the world and effective treatment is still not available. Over …

Extracellular deposition of amyloid-β as neuritic plaques and intracellular accumulation of
hyperphosphorylated, aggregated tau as neurofibrillary tangles are two of the characteristic …

Alzheimer's disease (AD) is a progressive and fatal neurodegenerative disorder. Impaired
neuronal bioenergetics and neuroinflammation are thought to play key roles in the …

Background Alzheimer's disease (AD) is a progressive neurodegenerative disorder
characterized by an abnormal accumulation of amyloid-β (Aβ) plaques, neuroinflammation …

As a result of brain injury, astrocytes become activated and start to proliferate in the vicinity
of the injury site. Recently, we had demonstrated that these reactive astrocytes, or glia, can …

Excessive mitochondrial fission is a prominent early event and contributes to mitochondrial
dysfunction, synaptic failure, and neuronal cell death in the progression of Alzheimer's …

Altered concentrations of amyloid-β (Aβ) peptide and Tau protein in the cerebrospinal fluid
(CSF) are thought to be predictive markers for Alzheimer's disease (AD). Transgenic mice …

Myelin loss is frequently observed in human Alzheimer's disease (AD) and may constitute to
AD‐related cognitive decline. A potential source to repair myelin defects are the …

Amyloid-β (Aβ) plaques, a hallmark of Alzheimer's disease (AD), are surrounded by regions
of neuronal and glial hyperactivity. We use in vivo two-photon and wide-field imaging of the …