Vitamin C in critically ill patients: an updated systematic review and meta-analysis

DB Shrestha, P Budhathoki, YR Sedhai, SK Mandal… - Nutrients, 2021 - mdpi.com
Background: Vitamin C is a water-soluble antioxidant vitamin. Oxidative stress and its
markers, along with inflammatory markers, are high during critical illness. Due to conflicting …

Vitamin C may improve left ventricular ejection fraction: a meta-analysis

H Hemilä, E Chalker, AME de Man - Frontiers in cardiovascular …, 2022 - frontiersin.org
Background Vitamin C deprivation can lead to fatigue, dyspnea, oedema and chest pain,
which are also symptoms of heart failure (HF). In animal studies vitamin C has improved …

[HTML][HTML] ESPEN micronutrient guideline

MM Berger, A Shenkin, A Schweinlin, K Amrein… - Clinical Nutrition, 2022 - Elsevier
Background Trace elements and vitamins, named together micronutrients (MNs), are
essential for human metabolism. Recent research has shown the importance of MNs in …

ESPEN practical short micronutrient guideline

MM Berger, A Shenkin, OS Dizdar, K Amrein… - Clinical Nutrition, 2024 - Elsevier
Background Trace elements and vitamins, named together micronutrients (MNs), are
essential for human metabolism. The importance of MNs in common pathologies is …

Vitamin C may reduce troponin and CKMB levels after PCI and CABG: a meta-analysis

S Rozemeijer, H Hemilä, M van Baaren… - BMC Cardiovascular …, 2023 - Springer
Background Ischemia/reperfusion injury contributes to periprocedural myocardial injury
(PMI) in patients undergoing percutaneous coronary intervention (PCI) or coronary artery …

Association of oral or intravenous vitamin C supplementation with mortality: a systematic review and meta-analysis

C Xu, T Yi, S Tan, H Xu, Y Hu, J Ma, J Xu - Nutrients, 2023 - mdpi.com
Mortality is the most clinically serious outcome, and its prevention remains a constant
struggle. This study was to assess whether intravenous or oral vitamin C (Vit-C) therapy is …

JLX001 improves myocardial ischemia-reperfusion injury by activating Jak2-Stat3 pathway

Q Yin, B Zhao, J Zhu, Y Fei, W Shen, B Liang, X Zhu… - Life Sciences, 2020 - Elsevier
Aims To investigate the preclinical pharmacodynamics and mechanism of JLX001 against
myocardial ischemia reperfusion (MI/R) for clinical application. Materials and methods In …

Vitamin C for cardiac protection during percutaneous coronary intervention: a systematic review of randomized controlled trials

SA Khan, S Bhattacharjee, MOA Ghani, R Walden… - Nutrients, 2020 - mdpi.com
Percutaneous coronary intervention (PCI) is the preferred treatment for acute coronary
syndrome (ACS) secondary to atherosclerotic coronary artery disease. This nonsurgical …

Low vitamin C status in patients with cancer is associated with patient and tumor characteristics

R White, M Nonis, JF Pearson, E Burgess, HR Morrin… - Nutrients, 2020 - mdpi.com
Vitamin C (ascorbate) acts as an antioxidant and enzyme cofactor, and plays a vital role in
human health. Vitamin C status can be affected by illness, with low levels being associated …

Combating ischemia-reperfusion injury with micronutrients and natural compounds during solid organ transplantation: Data of clinical trials and lessons of preclinical …

C Mauerhofer, L Grumet, P Schemmer, B Leber… - International Journal of …, 2021 - mdpi.com
Although extended donor criteria grafts bear a higher risk of complications such as graft
dysfunction, the exceeding demand requires to extent the pool of potential donors. The risk …