Single-nucleotide polymorphisms as important risk factors of diabetes among Middle East population

I Akhlaghipour, AR Bina, MR Mogharrabi, A Fanoodi… - Human Genomics, 2022 - Springer
Diabetes is a chronic metabolic disorder that leads to the dysfunction of various tissues and
organs, including eyes, kidneys, and cardiovascular system. According to the World Health …

Genetic risk of type 2 diabetes in populations of the African continent: A systematic review and meta-analyses

YY Yako, M Guewo-Fokeng, EV Balti… - Diabetes research and …, 2016 - Elsevier
Abstract Background Type 2 diabetes (T2D) is growing faster in Africa than anywhere else,
driven by the dual effects of genetic and environmental factors. We conducted a systematic …

Genetic polymorphisms in the Interleukins IL1B, IL4, and IL6 are associated with concomitant periodontitis and type 2 diabetes mellitus in Brazilian patients

T Cirelli, R Nepomuceno, ACS Rios… - Journal of …, 2020 - Wiley Online Library
Objective To assess whether single nucleotide polymorphisms (SNPs) in the IL10, IL1A,
IL1B, IL4, TNFA, IL6, OPG, RANK, and RANKL genes,“classically” related with periodontitis …

[HTML][HTML] The genetic polymorphisms and levels of adipokines and adipocytokines that influence the risk of developing gestational diabetes mellitus in Thai pregnant …

W Tangjittipokin, B Thanatummatis, F Wardati… - Gene, 2023 - Elsevier
Introduction Aberrant immune and inflammatory response is thought to be involved in the
pathogenesis of gestational diabetes mellitus (GDM). Objective To investigate the genetic …

CCL2, CCL5, IL4 and IL15 gene polymorphisms in women with gestational diabetes mellitus

J Teler, M Tarnowski, K Safranow… - Hormone and …, 2017 - thieme-connect.com
Gestational diabetes mellitus (GDM) is a glucose intolerance that occurs during pregnancy.
Several studies suggest that inflammation contributes to pregnancy-induced insulin …

Type 2 Diabetes Susceptibility in the Greek-Cypriot Population: Replication of Associations with TCF7L2, FTO, HHEX, SLC30A8 and IGF2BP2 Polymorphisms

C Votsi, C Toufexis, K Michailidou, A Antoniades… - Genes, 2017 - mdpi.com
Type 2 diabetes (T2D) has been the subject of numerous genetic studies in recent years
which revealed associations of the disease with a large number of susceptibility loci. We …

Genotyping of IL-4 −590 (C>T) Gene in Iraqi Asthma Patients

IA Hussein, SH Jaber - Disease markers, 2017 - Wiley Online Library
This study is the first investigation in Iraq dealing with genotyping of IL-4− 590 (C> T) gene,
especially in Iraqi patients with asthma. We studied forty‐eight blood samples collected from …

IL-13-1112 polymorphism and periodontitis susceptibility: a meta-analysis

W Zhang, P Xu, Z Chen, Y Cheng, X Li, Q Mao - BMC Oral Health, 2018 - Springer
Background Several studies have examined the association between the IL-13-1112C/T
polymorphism and the risk of periodontitis. However, these studies have reached different …

Evaluation of E-selectin rs 5367 C/T Polymorphism in Iraqi Diabetic Foot patients

MWM Alzubadiy, AMS Almohaidi… - Journal of Physics …, 2019 - iopscience.iop.org
Diabetic foot is inflammation disease, including inflammation factors; such as ESelectin. The
study aimed to evaluate E-selectin gene SNP rs 5367 C/T polymorphisms with other factors …

[HTML][HTML] Interleukin-4 (IL4)-590C/T (rs2243250) gene polymorphism is not associated with diabetic nephropathy (DN) in Caucasians with type 2 diabetes mellitus …

M Završnik, J Letonja, J Makuc, M Šeruga… - Bosnian Journal of …, 2018 - ncbi.nlm.nih.gov
Diabetic nephropathy (DN) is a microvascular complication that affects up to 40% of diabetic
patients and can lead to end-stage kidney disease. Inflammatory cytokines such as …