The transportome of the malaria parasite
RE Martin - Biological Reviews, 2020 - Wiley Online Library
Membrane transport proteins, also known as transporters, control the movement of ions,
nutrients, metabolites, and waste products across the membranes of a cell and are central to …
nutrients, metabolites, and waste products across the membranes of a cell and are central to …
[HTML][HTML] Comparative application of BioID and TurboID for protein-proximity biotinylation
BioID is a well-established method for identifying protein–protein interactions and has been
utilized within live cells and several animal models. However, the conventional labeling …
utilized within live cells and several animal models. However, the conventional labeling …
Multi-omics approaches to improve malaria therapy
Malaria contributes to the most widespread infectious diseases worldwide. Even though
current drugs are commercially available, the ever-increasing drug resistance problem by …
current drugs are commercially available, the ever-increasing drug resistance problem by …
[HTML][HTML] Mapping subcellular localizations of unannotated microproteins and alternative proteins with MicroID
Proteogenomic identification of translated small open reading frames has revealed
thousands of previously unannotated, largely uncharacterized microproteins, or …
thousands of previously unannotated, largely uncharacterized microproteins, or …
[HTML][HTML] Apicomplexan-like parasites are polyphyletic and widely but selectively dependent on cryptic plastid organelles
J Janouškovec, GG Paskerova, TS Miroliubova… - Elife, 2019 - elifesciences.org
The phylum Apicomplexa comprises human pathogens such as Plasmodium but is also an
under-explored hotspot of evolutionary diversity central to understanding the origins of …
under-explored hotspot of evolutionary diversity central to understanding the origins of …
Reconstruction of plastid proteomes of apicomplexans and close relatives reveals the major evolutionary outcomes of cryptic plastids
Apicomplexans and related lineages comprise many obligate symbionts of animals; some of
which cause notorious diseases such as malaria. They evolved from photosynthetic …
which cause notorious diseases such as malaria. They evolved from photosynthetic …
[HTML][HTML] Elucidating the mitochondrial proteome of Toxoplasma gondii reveals the presence of a divergent cytochrome c oxidase
A Seidi, LS Muellner-Wong, E Rajendran, ET Tjhin… - Elife, 2018 - elifesciences.org
The mitochondrion of apicomplexan parasites is critical for parasite survival, although the full
complement of proteins that localize to this organelle has not been defined. Here we …
complement of proteins that localize to this organelle has not been defined. Here we …
Metabolic quirks and the colourful history of the Euglena gracilis secondary plastid
Euglena spp. are phototrophic flagellates with considerable ecological presence and
impact. Euglena gracilis harbours secondary green plastids, but an incompletely …
impact. Euglena gracilis harbours secondary green plastids, but an incompletely …
Critical role for isoprenoids in apicoplast biogenesis by malaria parasites
M Okada, K Rajaram, RP Swift, A Mixon, JA Maschek… - Elife, 2022 - elifesciences.org
Isopentenyl pyrophosphate (IPP) is an essential metabolic output of the apicoplast organelle
in Plasmodium falciparum malaria parasites and is required for prenylation-dependent …
in Plasmodium falciparum malaria parasites and is required for prenylation-dependent …
Inner membrane complex proteomics reveals a palmitoylation regulation critical for intraerythrocytic development of malaria parasite
P Qian, X Wang, CQ Zhong, J Wang, M Cai… - Elife, 2022 - elifesciences.org
Malaria is caused by infection of the erythrocytes by the parasites Plasmodium. Inside the
erythrocytes, the parasites multiply via schizogony, an unconventional cell division mode …
erythrocytes, the parasites multiply via schizogony, an unconventional cell division mode …