Liver cancer, specifically hepatocellular carcinoma (HCC), is the sixth most common cancer
and the third leading cause of cancer mortality worldwide. The development of effective …

Dendritic cells (DCs) are professional antigen-presenting cells that play a key role in
shaping adaptive immunity. DCs have a unique ability to sample their environment, capture …

Simple Summary With the development of immunotherapies and targeted therapies in the
last years, there has been great progress in the outcome of patients with metastatic …

The approval of immune-checkpoint inhibitors (CPI) and mitogen activated protein kinase
inhibitors (MAPKi) in recent years significantly improved the treatment management and …

Purpose: Breast cancer is a highly heterogeneous malignancy, seriously threatening female
health worldwide and inducing higher mortalities. Few have the studies evaluated Fms-like …

The treatment of malignant melanoma has drastically changed over the past decade with the
advent of immune checkpoint blockade, targeted therapy with BRAF/MEK inhibition, and …

Toll-like receptors (TLRs) are indispensable for the activation, maintenance and halting of
immune responses. TLRs can mediate inflammation by recognizing molecular patterns in …

Breast cancer poses one of the largest threats to women's health. Treatment continues to
improve for all the subtypes of breast cancer, but some subtypes, such as triple negative …

Compelling evidence shows that the frequency of T cells in the tumor microenvironment
correlates with prognosis as well as response to immunotherapy. However, considerable …

In the emerging era of cancer immunotherapy, immune checkpoint blockades (ICBs) and
adoptive cell transfer therapies (ACTs) have gained significant attention. However, their …