Administration of anesthetic agents fundamentally shifts the responsibility for maintenance of
homeostasis from the patient and their intrinsic physiological regulatory mechanisms to the …

Abstract Cushing's disease (CD), or pituitary-dependent Cushing's syndrome, is a severe
endocrine disease caused by a corticotroph pituitary tumor and associated with increased …

Most general anaesthetics and classical benzodiazepine drugs act through positive
modulation of γ-aminobutyric acid type A (GABAA) receptors to dampen neuronal activity in …

Comprehensive, readable, and clinically oriented, Stoelting's Pharmacology & Physiology in
Anesthetic Practice, Sixth Edition, covers all aspects of pharmacology and physiology that …

Many patients who undergo general anesthesia and surgery experience cognitive
dysfunction, particularly memory deficits that can persist for days to months. The …

The repeating arrangement of tubulin dimers confers great mechanical strength to
microtubules, which are used as scaffolds for intracellular macromolecular transport in cells …

Management of glycemic levels in the perioperative setting is critical, especially in diabetic
patients. The effects of surgical stress and anesthesia have unique effects on blood glucose …

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Purpose We performed a meta-analysis of randomized controlled trials to evaluate if
etomidate impacted mortality in critically ill adults when compared with other induction …

Etomidate is a hypnotic agent that is used for the induction of anesthesia. It produces its
effect by acting as a positive allosteric modulator on the γ-aminobutyric acid type A receptor …