Mast cell-mediated mechanisms of nociception

A Aich, LB Afrin, K Gupta - International journal of molecular sciences, 2015 - mdpi.com
Mast cells are tissue-resident immune cells that release immuno-modulators, chemo-
attractants, vasoactive compounds, neuropeptides and growth factors in response to …

Inflammation induced by platelet-activating viperid snake venoms: perspectives on thromboinflammation

C Teixeira, CM Fernandes, E Leiguez… - Frontiers in …, 2019 - frontiersin.org
Envenomation by viperid snakes is characterized by systemic thrombotic syndrome and
prominent local inflammation. To date, the mechanisms underlying inflammation and blood …

Measuring changes in tactile sensitivity in the hind paw of mice using an electronic von Frey apparatus

T Martinov, M Mack, A Sykes… - Journal of visualized …, 2013 - pmc.ncbi.nlm.nih.gov
Measuring inflammation-induced changes in thresholds of hind paw withdrawal from
mechanical pressure is a useful technique to assess changes in pain perception in rodents …

Mast cells: versatile gatekeepers of pain

D Chatterjea, T Martinov - Molecular Immunology, 2015 - Elsevier
Mast cells are important first responders in protective pain responses that provoke
withdrawal from intense, noxious environmental stimuli, in part because of their sentinel …

[HTML][HTML] Contribution of metalloproteases, serine proteases and phospholipases A2 to the inflammatory reaction induced by Bothrops jararaca crude venom in mice

BC Zychar, CS Dale, DS Demarchi, LRC Gonçalves - Toxicon, 2010 - Elsevier
Various toxins isolated from Bothrops snake venoms induce inflammatory reactions and
have been claimed to contribute to the severity of local symptoms present in this …

[HTML][HTML] Comparative analysis of local effects caused by Bothrops alternatus and Bothrops moojeni snake venoms: enzymatic contributions and inflammatory …

CCN Mamede, BB de Sousa, DF da Cunha Pereira… - Toxicon, 2016 - Elsevier
Bothropic envenomation is characterised by severe local damage caused by the toxic action
of venom components and aggravated by induced inflammation. In this comparative study …

Alarmins and inflammatory aspects related to snakebite envenomation

JP Zuliani - Toxicon, 2023 - Elsevier
Snakebite envenoming is characterized by the injection of a mixture of proteins/toxins
present in venom following the bite of a venomous snake. The toxins have potent bioactivity …

Inflammatory mediators involved in the paw edema and hyperalgesia induced by Batroxase, a metalloproteinase isolated from Bothrops atrox snake venom

LGB De Toni, DL Menaldo, ACO Cintra… - International …, 2015 - Elsevier
Snake venom metalloproteinases have been described as responsible for several
inflammatory effects. In this study, we investigated the edema and hyperalgesia induced in …

[HTML][HTML] Contribution of mast cells to the oedema induced by Bothrops moojeni snake venom and a pharmacological assessment of the inflammatory mediators …

NG Nascimento, MC Sampaio, RA Olivo, C Teixeira - Toxicon, 2010 - Elsevier
The ability of Bothrops moojeni venom (BmV) to induce oedema in mice, the involvement of
principal inflammatory mediators and mast cells (MCs) were investigated. The intraplantar …

Overview and controversies in the medical management of pit viper envenomation in the dog

RA Armentano, M Schaer - Journal of Veterinary Emergency …, 2011 - Wiley Online Library
Objective To provide a review and update on the medical management of pit viper
envenomation in dogs. Etiology Pit viper snake (C rotalidae) envenomation in dogs is a …