Advances in engineering human tissue models
CM Moysidou, C Barberio, RM Owens - Frontiers in bioengineering …, 2021 - frontiersin.org
Research in cell biology greatly relies on cell-based in vitro assays and models that facilitate
the investigation and understanding of specific biological events and processes under …
the investigation and understanding of specific biological events and processes under …
Toward building the neuromuscular junction: in vitro models to study synaptogenesis and neurodegeneration
A Natarajan, A Sethumadhavan, UM Krishnan - ACS omega, 2019 - ACS Publications
The neuromuscular junction (NMJ) is a unique, specialized chemical synapse that plays a
crucial role in transmitting and amplifying information from spinal motor neurons to skeletal …
crucial role in transmitting and amplifying information from spinal motor neurons to skeletal …
Neuromuscular disease modeling on a chip
JW Santoso, ML McCain - Disease models & mechanisms, 2020 - journals.biologists.com
Organs-on-chips are broadly defined as microfabricated surfaces or devices designed to
engineer cells into microscale tissues with native-like features and then extract …
engineer cells into microscale tissues with native-like features and then extract …
Combinatorial biophysical cue sensor array for controlling neural stem cell fate
Biophysical cues, such as electrical stimulus, mechanical feature, and surface topography,
enable the control of neural stem cell (NSC) differentiation and neurite outgrowth. However …
enable the control of neural stem cell (NSC) differentiation and neurite outgrowth. However …
In vitro models of neuromuscular junctions and their potential for novel drug discovery and development
ABSTRACT Introduction: Neuromuscular Junctions (NMJs) are the synapses between motor
neurons and skeletal muscle fibers, and they are responsible for voluntary motor function …
neurons and skeletal muscle fibers, and they are responsible for voluntary motor function …
Creating stem cell‐derived neuromuscular junctions in vitro
Recent development of novel therapies has improved mobility and quality of life for people
suffering from inheritable neuromuscular disorders. Despite this progress, the majority of …
suffering from inheritable neuromuscular disorders. Despite this progress, the majority of …
Modeling the neuromuscular junction in vitro: an approach to study neuromuscular junction disorders
MJ Castellanos‐Montiel, I Velasco… - Annals of the New …, 2021 - Wiley Online Library
The neuromuscular junction (NMJ) is a specialized structure that works as an interface to
translate the action potential of the presynaptic motor neuron (MN) in the contraction of the …
translate the action potential of the presynaptic motor neuron (MN) in the contraction of the …
Optimization of Application-Driven Development of In Vitro Neuromuscular Junction Models
JB Strickland, K Davis-Anderson… - … Engineering Part B …, 2022 - liebertpub.com
Neuromuscular junctions (NMJs) are specialized synapses responsible for signal
transduction between motor neurons (MNs) and skeletal muscle tissue. Malfunction at this …
transduction between motor neurons (MNs) and skeletal muscle tissue. Malfunction at this …
Challenges and Future Prospects on 3D in-vitro Modeling of the Neuromuscular Circuit
M Badiola-Mateos, A Hervera, JA Del Rio… - … in bioengineering and …, 2018 - frontiersin.org
Movement of skeletal-muscle fibers is generated by the coordinated action of several cells
taking part within the locomotion circuit (motoneurons, sensory-neurons, Schwann cells …
taking part within the locomotion circuit (motoneurons, sensory-neurons, Schwann cells …
Voltage-gated calcium channels as potential therapeutic targets in migraine
Migraine is a complex and highly incapacitating neurological disorder that affects around
15% of the general population with greater incidence in women, often at the most productive …
15% of the general population with greater incidence in women, often at the most productive …