Overview of the mechanisms that may contribute to the non-redundant activities of interferon-inducible CXC chemokine receptor 3 ligands

M Metzemaekers, V Vanheule, R Janssens… - Frontiers in …, 2018 - frontiersin.org
The inflammatory chemokines CXCL9, CXCL10, and CXCL11 are predominantly induced
by interferon (IFN)-γ and share an exclusive chemokine receptor named CXC chemokine …

Regulatory T cell plasticity and stability and autoimmune diseases

R Qiu, L Zhou, Y Ma, L Zhou, T Liang, L Shi… - Clinical reviews in …, 2020 - Springer
Abstract CD4+ CD25+ regulatory T cells (Tregs) are a class of CD4+ T cells with
immunosuppressive functions that play a critical role in maintaining immune homeostasis …

Frontline Science: Abnormalities in the gut mucosa of non-obese diabetic mice precede the onset of type 1 diabetes

MCG Miranda, RP Oliveira, L Torres… - Journal of Leukocyte …, 2019 - academic.oup.com
Alterations in the composition of the intestinal microbiota have been associated with
development of type 1 diabetes (T1D), but little is known about changes in intestinal …

Development of Type 1 Diabetes in Mice Is Associated with a Decrease in IL-2-Producing ILC3 and FoxP3+ Treg in the Small Intestine

T Saksida, V Paunović, I Koprivica, D Mićanović… - Molecules, 2023 - mdpi.com
Recent data indicate the link between the number and function of T regulatory cells (Treg) in
the gut immune tissue and initiation and development of autoimmunity associated with type …

Modulation of intestinal ILC3 for the treatment of type 1 diabetes

I Stojanović, T Saksida, Đ Miljković… - Frontiers in …, 2021 - frontiersin.org
Gut-associated lymphoid tissue (GALT) is crucial for the maintenance of the intestinal
homeostasis, but it is also the potential site of the activation of autoreactive cells and …

Salivary levels of hBDs in children and adolescents with type 1 diabetes mellitus and gingivitis

D Yilmaz, N Yilmaz, R Polat, V Nissilä, EG Aydın… - Clinical Oral …, 2022 - Springer
Objectives Type 1 diabetes mellitus (T1DM), a chronic autoimmune disease characterized
by insulin deficiency, is related to periodontal diseases in children and adolescents. Our aim …

ILC3: a case of conflicted identity

I Koprivica, S Stanisavljević, D Mićanović… - Frontiers in …, 2023 - frontiersin.org
Innate lymphoid cells type 3 (ILC3s) are the first line sentinels at the mucous tissues, where
they contribute to the homeostatic immune response in a major way. Also, they have been …

Latent autoimmune diabetes in adults (LADA): from immunopathogenesis to Immunotherapy

J Hu, R Zhang, H Zou, L Xie, Z Zhou… - Frontiers in …, 2022 - frontiersin.org
Latent autoimmune diabetes in adults (LADA) is a type of diabetes characterized by slow
autoimmune damage of pancreatic β cells without insulin treatment in the early clinical …

Altered expression of CD39 on memory regulatory T cells in type 1 diabetes patients

X Jin, C Zhang, L Gong, H Li, Y Wang, Q Li… - Journal of …, 2019 - Wiley Online Library
Abstract Background Type 1 diabetes (T1D) is an autoimmune disease resulting from an
attack by autoreactive T lymphocytes against pancreatic islet β‐cells. In recent studies …

Negative correlation between circulating integrin Α4+ group 3 innate Lymphoid cells and the severity of type 2 diabetes

YP Zhuang, ZY Pan, JM Huang, HG Zhou… - International …, 2023 - Elsevier
Background Impaired intestinal barrier and immune dysfunction promote the development of
type 2 diabetes (T2D). Group 3 innate lymphoid cells (ILC3s), which are enriched in the …