Crossing the blood-brain barrier: advances in nanoparticle technology for drug delivery in neuro-oncology
The blood-brain barrier (BBB) constitutes a microvascular network responsible for excluding
most drugs from the brain. Treatment of brain tumors is limited by the impermeability of the …
most drugs from the brain. Treatment of brain tumors is limited by the impermeability of the …
[HTML][HTML] Progress and perspectives on targeting nanoparticles for brain drug delivery
H Gao - Acta Pharmaceutica Sinica B, 2016 - Elsevier
Due to the ability of the blood–brain barrier (BBB) to prevent the entry of drugs into the brain,
it is a challenge to treat central nervous system disorders pharmacologically. The …
it is a challenge to treat central nervous system disorders pharmacologically. The …
Endohedral fullerenes
AA Popov, S Yang, L Dunsch - Chemical reviews, 2013 - ACS Publications
One of the attractive properties of the hollow carbon clusters, known as fullerenes, is the
possibility to use them as robust containers for other species. Although an IUPAC …
possibility to use them as robust containers for other species. Although an IUPAC …
When metal clusters meet carbon cages: endohedral clusterfullerenes
S Yang, T Wei, F Jin - Chemical society reviews, 2017 - pubs.rsc.org
Fullerenes have the characteristic of a hollow interior, and this unique feature triggers
intuitive inspiration to entrap atoms, ions or clusters inside the carbon cage in the form of …
intuitive inspiration to entrap atoms, ions or clusters inside the carbon cage in the form of …
Bioanalytical chemistry of cytokines–a review
JA Stenken, AJ Poschenrieder - Analytica chimica acta, 2015 - Elsevier
Cytokines are bioactive proteins produced by many different cells of the immune system.
Due to their role in different inflammatory disease states and maintaining homeostasis, there …
Due to their role in different inflammatory disease states and maintaining homeostasis, there …
Current status and future developments of endohedral metallofullerenes
X Lu, L Feng, T Akasaka, S Nagase - Chemical Society Reviews, 2012 - pubs.rsc.org
Endohedral metallofullerenes (EMFs), a new class of hybrid molecules formed by
encapsulation of metallic species inside fullerene cages, exhibit unique properties that differ …
encapsulation of metallic species inside fullerene cages, exhibit unique properties that differ …
Ligand modified nanoparticles increases cell uptake, alters endocytosis and elevates glioma distribution and internalization
Nanoparticles (NPs) were widely used in drugs/probes delivery for improved disease
diagnosis and/or treatment. Targeted delivery to cancer cells is a highly attractive application …
diagnosis and/or treatment. Targeted delivery to cancer cells is a highly attractive application …
Cancer‐targeted nanomedicine: overcoming the barrier of the protein corona
Nanomedicines exploit the unusual physicochemical and biological properties of
nanoparticles, including their nanoscopic size, high surface‐area‐to‐volume ratio, easy …
nanoparticles, including their nanoscopic size, high surface‐area‐to‐volume ratio, easy …
Fullerenes for the treatment of cancer: an emerging tool
NB Fernandes, RUK Shenoy, MK Kajampady… - … Science and Pollution …, 2022 - Springer
Cancer is a most common cause of mortality globally. Available medicines possess severe
side effects owing to their non-specific targeting. Hence, there is a need of an alternative in …
side effects owing to their non-specific targeting. Hence, there is a need of an alternative in …
[HTML][HTML] Applications of functionalized fullerenes in tumor theranostics
Functionalized fullerenes with specific physicochemical properties have been developed for
cancer diagnosis and therapy. Notably, metallofullerene is a new class of magnetic …
cancer diagnosis and therapy. Notably, metallofullerene is a new class of magnetic …