Crossing the blood-brain barrier: advances in nanoparticle technology for drug delivery in neuro-oncology

AM Hersh, S Alomari, BM Tyler - International journal of molecular …, 2022 - mdpi.com
The blood-brain barrier (BBB) constitutes a microvascular network responsible for excluding
most drugs from the brain. Treatment of brain tumors is limited by the impermeability of the …

[HTML][HTML] Progress and perspectives on targeting nanoparticles for brain drug delivery

H Gao - Acta Pharmaceutica Sinica B, 2016 - Elsevier
Due to the ability of the blood–brain barrier (BBB) to prevent the entry of drugs into the brain,
it is a challenge to treat central nervous system disorders pharmacologically. The …

Endohedral fullerenes

AA Popov, S Yang, L Dunsch - Chemical reviews, 2013 - ACS Publications
One of the attractive properties of the hollow carbon clusters, known as fullerenes, is the
possibility to use them as robust containers for other species. Although an IUPAC …

When metal clusters meet carbon cages: endohedral clusterfullerenes

S Yang, T Wei, F Jin - Chemical society reviews, 2017 - pubs.rsc.org
Fullerenes have the characteristic of a hollow interior, and this unique feature triggers
intuitive inspiration to entrap atoms, ions or clusters inside the carbon cage in the form of …

Bioanalytical chemistry of cytokines–a review

JA Stenken, AJ Poschenrieder - Analytica chimica acta, 2015 - Elsevier
Cytokines are bioactive proteins produced by many different cells of the immune system.
Due to their role in different inflammatory disease states and maintaining homeostasis, there …

Current status and future developments of endohedral metallofullerenes

X Lu, L Feng, T Akasaka, S Nagase - Chemical Society Reviews, 2012 - pubs.rsc.org
Endohedral metallofullerenes (EMFs), a new class of hybrid molecules formed by
encapsulation of metallic species inside fullerene cages, exhibit unique properties that differ …

Ligand modified nanoparticles increases cell uptake, alters endocytosis and elevates glioma distribution and internalization

H Gao, Z Yang, S Zhang, S Cao, S Shen, Z Pang… - Scientific reports, 2013 - nature.com
Nanoparticles (NPs) were widely used in drugs/probes delivery for improved disease
diagnosis and/or treatment. Targeted delivery to cancer cells is a highly attractive application …

Cancer‐targeted nanomedicine: overcoming the barrier of the protein corona

AK Barui, JY Oh, B Jana, C Kim… - Advanced therapeutics, 2020 - Wiley Online Library
Nanomedicines exploit the unusual physicochemical and biological properties of
nanoparticles, including their nanoscopic size, high surface‐area‐to‐volume ratio, easy …

Fullerenes for the treatment of cancer: an emerging tool

NB Fernandes, RUK Shenoy, MK Kajampady… - … Science and Pollution …, 2022 - Springer
Cancer is a most common cause of mortality globally. Available medicines possess severe
side effects owing to their non-specific targeting. Hence, there is a need of an alternative in …

[HTML][HTML] Applications of functionalized fullerenes in tumor theranostics

Z Chen, L Ma, Y Liu, C Chen - Theranostics, 2012 - ncbi.nlm.nih.gov
Functionalized fullerenes with specific physicochemical properties have been developed for
cancer diagnosis and therapy. Notably, metallofullerene is a new class of magnetic …