Protein misfolding and aggregation, a key contributor to the progression of numerous
neurodegenerative diseases, results in functional deficiencies and the creation of harmful …

Amyloid fibrils are β-sheet rich protein aggregates that are strongly associated with various
neurodegenerative diseases. Raman spectroscopy has been broadly utilized to investigate …

Starting with a historical account of evolution in Raman spectroscopy, in this review we
provide details of the advancements that have pushed detection limits to single molecules …

Strategies for protein detection via surface-enhanced Raman spectroscopy (SERS) currently
exploit the formation of randomly generated hot spots at the interfaces of metal colloidal …

Surface-enhanced Raman scattering (SERS) is a powerful analytic tool that can provide
information of molecular structures and composition of analytes. The application of SERS for …

Abnormal aggregation of amyloid‐β is a very complex and heterogeneous process. Owing
to methodological limitations, the aggregation pathway is still not fully understood. Herein a …

Spontaneous aggregation of misfolded proteins typically results in the formation of
morphologically and structurally different amyloid fibrils, protein aggregates that are strongly …

It has been proposed that a “common core” of pathologic pathways exists for the large family
of amyloid-associated neurodegenerations, including Alzheimer's, Parkinson's, type II …

For a very long period, tin was considered one of the most important metals for humans due
to its easy access in nature and abundance of sources. In the past, tin was mainly used to …

Abnormal protein aggregation has been intensively studied for over 40 years and broadly
discussed in the literature due to its significant role in neurodegenerative diseases etiology …