Recent progress in functionalized and targeted polymersomes and chimeric polymeric nanotheranostic platforms for cancer therapy

M Beygi, F Oroojalian, SS Hosseini… - Progress in Materials …, 2023 - Elsevier
The majority of advances in cancer therapy have been achieved based on developments in
public awareness, as well as novel diagnostic and therapeutic modalities. Treatment …

Three-dimensional in vitro tumor spheroid models for evaluation of anticancer therapy: recent updates

P Nayak, V Bentivoglio, M Varani, A Signore - Cancers, 2023 - mdpi.com
Simple Summary Cancer is a global public health issue. The development and use of in vitro
cellular models with pre-clinical animal models are essential to elucidate the complex …

Trastuzumab Conjugated Superparamagnetic Iron Oxide Nanoparticles Labeled with 225Ac as a Perspective Tool for Combined α-Radioimmunotherapy and …

E Cędrowska, M Pruszyński, W Gawęda, M Żuk… - Molecules, 2020 - mdpi.com
It has been proven and confirmed in numerous repeated tests, that the use of a combination
of several therapeutic methods gives much better treatment results than in the case of …

[HTML][HTML] A perspective on the radiopharmaceutical requirements for imaging and therapy of glioblastoma

J Bolcaen, J Kleynhans, S Nair, J Verhoeven… - Theranostics, 2021 - ncbi.nlm.nih.gov
Despite numerous clinical trials and pre-clinical developments, the treatment of glioblastoma
(GB) remains a challenge. The current survival rate of GB averages one year, even with an …

Review of therapeutic applications of radiolabeled functional nanomaterials

J Jeon - International journal of molecular sciences, 2019 - mdpi.com
In the last two decades, various nanomaterials have attracted increasing attention in medical
science owing to their unique physical and chemical characteristics. Incorporating …

[HTML][HTML] In vitro biomimetic models for glioblastoma-a promising tool for drug response studies

T Stanković, T Ranđelović, M Dragoj, SS Burić… - Drug Resistance …, 2021 - Elsevier
The poor response of glioblastoma to current treatment protocols is a consequence of its
intrinsic drug resistance. Resistance to chemotherapy is primarily associated with …

Three-dimensional cell culture systems in radiopharmaceutical cancer research

A Doctor, V Seifert, M Ullrich, S Hauser, J Pietzsch - Cancers, 2020 - mdpi.com
Simple Summary Cancer cells cultured in three-dimensional (3D) model systems exhibit
physiologically relevant cell–cell and cell–matrix interactions, gene expression patterns, and …

Tumor grafted–chick chorioallantoic membrane as an alternative model for biological cancer research and conventional/nanomaterial-based theranostics evaluation

AK Mapanao, PP Che, P Sarogni, P Sminia… - Expert Opinion on …, 2021 - Taylor & Francis
Introduction: Advancements in cancer management and treatment are associated with
strong preclinical research data, in which reliable cancer models are demanded. Indeed …

The in vivo fate of 225Ac daughter nuclides using polymersomes as a model carrier

RM Kruijff, R Raavé, A Kip, J Molkenboer-Kuenen… - Scientific reports, 2019 - nature.com
Increasing attention is given to personalized tumour therapy, where α-emitters can
potentially play an important role. Alpha particles are ideal for localized cell killing because …

Nanoparticles in targeted alpha therapy

A Majkowska-Pilip, W Gawęda… - Nanomaterials, 2020 - mdpi.com
Recent advances in the field of nanotechnology application in nuclear medicine offer the
promise of better therapeutic options. In recent years, increasing efforts have been made on …