When light is incident to a biological tissue surface, combinations of optical processes occur,
such as reflection, absorption, elastic and non-elastic scattering, and fluorescence. Analysis …

While our understanding of vulnerable coronary plaque is still at an early stage, the concept
that certain types of plaques predispose patients to developing an acute myocardial …

There is an ever-increasing demand for new imaging methods that can provide additional
information about the coronary wall to better characterize and stratify high-risk plaques, and …

In this paper we have used second harmonic generation (SHG) and phasor approach to
auto fluorescence lifetime imaging (FLIM) to obtain fingerprints of different collagens and …

The rupture of vulnerable atherosclerotic plaque accounts for the majority of clinically
significant acute cardiovascular events. Because stability of these culprit lesions is directly …

2007-11-13 Assigned to SEARETE, LLC reassignment SEARETE, LLC ASSIGNMENT OF
ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: WEAVER, THOMAS …

The autofluorescence of biological tissue can be exploited for the detection and diagnosis of
disease but, to date, its complex nature and relatively weak signal levels have impeded its …

OBJECTIVE: Plaque with dense inflammatory cells, including macrophages, thin fibrous cap
and superficial necrotic/lipid core is thought to be prone-to-rupture. We report a time …

Comprehensive imaging of both the structural and biochemical characteristics of
atherosclerotic plaque is essential for the diagnosis and study of coronary artery disease …

Early detection and treatment of rupture-prone vulnerable atherosclerotic plaques is critical
to reducing patient mortality associated with cardiovascular disease. The combination of …