Depression is the most common mental disorder and a leading cause of disability
worldwide. Despite abundant research, the precise mechanisms underlying the …

Gut microbes and their metabolites are actively involved in the development and regulation
of host immunity, which can influence disease susceptibility. Herein, we review the most …

Critically ill patients in intensive care units experience profound alterations of their gut
microbiota that have been linked to a high risk of hospital-acquired (nosocomial) infections …

The microbiomes of cesarean-born infants differ from vaginally delivered infants and are
associated with increased disease risks. Vaginal microbiota transfer (VMT) to newborns may …

Perturbations to the infant gut microbiome during the first weeks to months of life affect
growth, development and health. In particular, assembly of an altered intestinal microbiota …

The second and third trimesters of pregnancy are crucial for the anatomical and functional
development of the gastrointestinal (GI) tract. If premature birth occurs, the immaturity of the …

The blood–brain barrier (BBB) protects the central nervous system from infections or harmful
substances; its impairment can lead to or exacerbate various diseases of the central nervous …

Exposure to synthetic and natural chemicals is a major environmental risk factor in the
etiology of many chronic diseases. Investigating complex co-exposures is necessary for a …

The early life microbiome plays critical roles in host development, shaping long-term
outcomes including brain functioning. It is not known which initial infant colonizers elicit …

Importance The effects of probiotic interventions on colonization with resistant bacteria and
early microbiome development in preterm infants remain to be clarified. Objective To …