Thiazolidinedione (TZD) is one of the privileged heterocyclic rings and has shown many
biological applications in medicinal chemistry and drug discovery. This review covers the …

Abstract Novel series of 5-benzylidenethiazolidine-2, 4-dione derivatives 4 ac-8 af were
designed, synthesized and evaluated for anticancer activity against HepG2, HCT-116 and …

Thiazolidinedione (2, 4‐TZD), commonly known as glitazone, is a ubiquitous heterocyclic
pharmacophore possessing a plethora of pharmacological activities and offering a vast …

As the ninth leading cause of death globally, diabetes mellitus (DM) is considered to be the
worst chronic metabolic disease requiring an enormous need for healthcare with over 578 …

This work aimed to synthesize safe antihyperglycemic derivatives bearing thiazolidinedione
fragment based on spectral data. The DFT theory discussed the frontier molecular orbitals …

Diabetes mellitus is a chronic metabolic disorder become a major health problem globally
associated with social and economic consequences. α-amylase is an endo-amylase …

Novel derivatives of Mycosidine (3, 5-substituted thiazolidine-2, 4-diones) are synthesized
by Knoevenagel condensation and reactions of thiazolidines with chloroformates or halo …

Abstract α-amylase enzyme hydrolyses carbohydrate into glucose is known to be an
important molecular target for type 2 Diabetes mellitus. In the course of developing α …

A new Schiff base ligand, 2-((Z)-(4-((furan-2-ylmethylene) amino)-1, 5-dimethyl-2-phenyl-1H-
pyrazol-3 (2H)-ylidene) amino) pyridine-3-ol have been synthesized by the condensation of …

A new Schiff base ligand of 2-(((3Z)-1, 5-dimethyl-2-phenyl-4-((thiophen-2-ylmethylene)
amino)-1, 2-dihydro-3H-pyrazol-3-ylidene) amino) pyridin-3-ol is prepared and some metal …