The aetiology of systemic lupus erythematosus (SLE) is multifactorial, and includes
contributions from the environment, stochastic factors, and genetic susceptibility. Great gains …

Glucocorticoids regulate fundamental processes of the human body and control cellular
functions such as cell metabolism, growth, differentiation, and apoptosis. Moreover …

These guidelines are a consensus work of a considerable number of members of the
immunology and flow cytometry community. They provide the theory and key practical …

From a technical point of view a flow cytometer is a light detection device capable of
detecting photons of different wavelengths over a high dynamic range. In order to achieve a …

Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by loss of
tolerance to nucleic acids and highly diverse clinical manifestations. To assess its molecular …

B cells play a central role in the immunopathogenesis of glomerulonephritides and
transplant rejection. B cells secrete antibodies that contribute to tissue injury via multiple …

Acute systemic lupus erythematosus (SLE) courses with surges of antibody-secreting cells
(ASCs) whose origin, diversity and contribution to serum autoantibodies remain unknown …

The third edition of Flow Cytometry Guidelines provides the key aspects to consider when
performing flow cytometry experiments and includes comprehensive sections describing …

Systemic lupus erythematosus, Sjögren's syndrome, and dermatomyositis are systemic
autoimmune diseases that develop after environmental triggering of genetically susceptible …

Objectives We examined the utility of circulating total and IgG4+ plasmablasts as biomarkers
of diagnosis and disease activity in IgG4-related disease (IgG4-RD). Materials methods We …