[HTML][HTML] Cell or cell membrane-based drug delivery systems

S Tan, T Wu, D Zhang, Z Zhang - Theranostics, 2015 - ncbi.nlm.nih.gov
Natural cells have been explored as drug carriers for a long period. They have received
growing interest as a promising drug delivery system (DDS) until recently along with the …

Engineered bacterial membrane vesicles are promising carriers for vaccine design and tumor immunotherapy

Q Long, P Zheng, X Zheng, W Li, L Hua, Z Yang… - Advanced drug delivery …, 2022 - Elsevier
Bacterial membrane vesicles (BMVs) have emerged as novel and promising platforms for
the development of vaccines and immunotherapeutic strategies against infectious and …

Applying extracellular vesicles based therapeutics in clinical trials–an ISEV position paper

T Lener, M Gimona, L Aigner, V Börger… - Journal of …, 2015 - Taylor & Francis
Extracellular vesicles (EVs), such as exosomes and microvesicles, are released by different
cell types and participate in physiological and pathophysiological processes. EVs mediate …

Outer membrane vesicles as platform vaccine technology

L Van Der Pol, M Stork, P van der Ley - Biotechnology journal, 2015 - Wiley Online Library
Outer membrane vesicles (OMVs) are released spontaneously during growth by many Gram‐
negative bacteria. They present a range of surface antigens in a native conformation and …

Peptide-based vaccines for tuberculosis

W Gong, C Pan, P Cheng, J Wang, G Zhao… - Frontiers in …, 2022 - frontiersin.org
Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis. As a
result of the coronavirus disease 2019 (COVID-19) pandemic, the global TB mortality rate in …

Extracellular vesicles as an efficient and versatile system for drug delivery

XTT Dang, JM Kavishka, DX Zhang, M Pirisinu, MTN Le - Cells, 2020 - mdpi.com
Despite the recent advances in drug development, the majority of novel therapeutics have
not been successfully translated into clinical applications. One of the major factors hindering …

Controlled human infection models to accelerate vaccine development

RKM Choy, AL Bourgeois… - Clinical Microbiology …, 2022 - Am Soc Microbiol
The timelines for developing vaccines against infectious diseases are lengthy, and often
vaccines that reach the stage of large phase 3 field trials fail to provide the desired level of …

Outer membrane vesicles for vaccination and targeted drug delivery

S Wang, J Gao, Z Wang - Wiley Interdisciplinary Reviews …, 2019 - Wiley Online Library
Extracellular vesicles (EVs) are cell membrane‐derived compartments that spontaneously
secrete from a wide range of cells and tissues. EVs have shown to be the carriers in …

Exosomes in diagnostic and therapeutic applications: biomarker, vaccine and RNA interference delivery vehicle

C Lässer - Expert opinion on biological therapy, 2015 - Taylor & Francis
Introduction: Cells release extracellular vesicles to their surroundings to communicate with
each other. Exosomes are a subgroup of 30–100-nm-sized extracellular vesicles, originating …

Bacterial membrane vesicles, an overlooked environmental colloid: biology, environmental perspectives and applications

M Toyofuku, Y Tashiro, Y Hasegawa… - Advances in Colloid and …, 2015 - Elsevier
Phospholipid vesicles play important roles in biological systems. Bacteria are one of the
most abundant organisms on Earth, and bacterial membrane vesicles (MVs) were first …