The reorganization of metabolic pathways in cancer facilitates the flux of carbon and
reducing equivalents into anabolic pathways at the expense of oxidative phosphorylation …

All cancers tested so far display abnormal choline and ethanolamine phospholipid
metabolism, which has been detected with numerous magnetic resonance spectroscopy …

Activated choline metabolism is a hallmark of carcinogenesis and tumor progression, which
leads to elevated levels of phosphocholine and glycerophosphocholine in all types of …

Integrins are important regulators of cell survival, proliferation, adhesion and migration.
Once activated, integrins establish a regulated link between the extracellular matrix and the …

Abnormal choline metabolism continues to be identified in multiple cancers. Molecular
causes of abnormal choline metabolism are changes in choline kinase-α, ethanolamine …

Skeletal muscle plays a central role in the regulation of systemic metabolism during lifespan.
With aging, this function is perturbed, initiating multiple chronic diseases. Our knowledge of …

Mitophagy, which selectively eliminates the dysfunctional and excess mitochondria by
autophagy, is crucial for cellular homeostasis under stresses such as hypoxia. Dysregulation …

Metabolic rearrangements subsequent to malignant transformation are not well
characterized in endometrial cancer. Identification of altered metabolites could facilitate …

Sunitinib resistance is a major challenge in systemic therapy for renal cell carcinoma (RCC).
The role of circular RNAs (circRNAs) in regulating sunitinib resistance of RCC is largely …

Colorectal cancer is one of the main causes of cancer death worldwide, and novel
biomarkers are urgently needed for its early diagnosis and treatment. The utilization of …