Squamous cell carcinomas of the head and neck (SCCHN) are associated strongly with the
use of tobacco and alcohol, but little is known about the molecular pathogenesis of these …

Background. Malignant soft-tissue tumors often present substantial diagnostic challenges.
Chromosome aberrations that might be diagnostic have been identified in some types of soft …

The cytogenetic patterns of uterine leiomyomas have been extensively investigated, and
cases characterized by specific clonal changes have been documented in detail. In these …

Synovial chondromatosis is a rare lesion, which is still believed by most authors to be
reactive rather than neoplastic. We report on a case of synovial chondromatosis with clonal …

None of the vector systems currently available for gene therapy applications have been
shown to be capable of both efficient gene transfer into nondividing cells and long-term …

Meningioma is the most frequent tumor of neuroectodermal origin in humans. It is usually
benign. Only a minority of cases shows progression to an anaplastic tumor (WHO grade II …

Extra abnormal chromosomes (rings and giant rods) containing chromosome 12 sequences
are characteristic of well‐differentiated liposarcoma (WDLPS). By whole chromosome …

PTPG, the gene for protein-tyrosine phosphatase gamma (PTP gamma), maps to a region of
human chromosome 3, 3p21, that is frequently deleted in renal cell carcinoma and lung …

A translocation that involves chromosome X (band p11. 2) and chromosome 18 (band q11.
2) was observed in short-term in vitro cultures of cells from five synovial sarcomas and one …

Detailed chromosome studies, briefly reported previously, from short-term cultures of tumor
cells from myxoid liposarcomas are reported. A common reciprocal translocation, t (12; …