Topology of three-dimensional active nematic turbulence confined to droplets

S Čopar, J Aplinc, Ž Kos, S Žumer, M Ravnik - Physical Review X, 2019 - APS
Active nematics contain topological defects that (under sufficient activity) move, create, and
annihilate in a chaotic quasi-steady state, called active turbulence. However, understanding …

[HTML][HTML] Liquid-crystal organization of liver tissue

H Morales-Navarrete, H Nonaka, A Scholich… - Elife, 2019 - elifesciences.org
Functional tissue architecture originates by self-assembly of distinct cell types, following
tissue-specific rules of cell-cell interactions. In the liver, a structural model of the lobule was …

[HTML][HTML] Anisotropic expansion of hepatocyte lumina enforced by apical bulkheads

L Belicova, U Repnik, J Delpierre, E Gralinska… - Journal of Cell …, 2021 - rupress.org
Lumen morphogenesis results from the interplay between molecular pathways and
mechanical forces. In several organs, epithelial cells share their apical surfaces to form a …

Learning developmental mode dynamics from single-cell trajectories

N Romeo, A Hastewell, A Mietke, J Dunkel - Elife, 2021 - elifesciences.org
Embryogenesis is a multiscale process during which developmental symmetry breaking
transitions give rise to complex multicellular organisms. Recent advances in high-resolution …

[HTML][HTML] Resilience of three-dimensional sinusoidal networks in liver tissue

J Karschau, A Scholich, J Wise… - PLoS computational …, 2020 - journals.plos.org
Can three-dimensional, microvasculature networks still ensure blood supply if individual
links fail? We address this question in the sinusoidal network, a plexus-like microvasculature …

Induction of Bile Canaliculi-Forming Hepatocytes from Human Pluripotent Stem Cells

L Matakovic, AW Overeem, K Klappe… - … : Methods and Protocols, 2022 - Springer
Cell polarity and formation of bile canaliculi can be achieved in hepatocytes which are
generated from patient-derived induced pluripotent stem cells. This allows for the study of …

Curvature strains as a global orchestrator of morphogenesis

JB Kirkegaard - Physical Review Research, 2022 - APS
Successful morphogenesis on the scale of organs or organisms requires strict coordination
between the constituent cells whose action on the local scale must be orchestrated …

Geometry and transport in development

NF Romeo - 2023 - dspace.mit.edu
Shape changes are some of the most visually striking features of biological development at
all scales of living matter. With recent advances in high-resolution microscopy, it becomes …

Network permeability changes according to a quadratic power law upon removal of a single edge

S Lange, BM Friedrich - Europhysics Letters, 2021 - iopscience.iop.org
We report a phenomenological power law for the reduction of network permeability in
statistically homogeneous spatial networks upon removal of a single edge. We characterize …

Correction: Quantification of nematic cell polarity in three-dimensional tissues

A Scholich, S Syga, H Morales-Navarrete… - PLoS Computational …, 2021 - journals.plos.org
Correction: Quantification of nematic cell polarity in three-dimensional tissues Page 1 CORRECTION
Correction: Quantification of nematic cell polarity in three-dimensional tissues André Scholich …