Topology of three-dimensional active nematic turbulence confined to droplets
Active nematics contain topological defects that (under sufficient activity) move, create, and
annihilate in a chaotic quasi-steady state, called active turbulence. However, understanding …
annihilate in a chaotic quasi-steady state, called active turbulence. However, understanding …
[HTML][HTML] Liquid-crystal organization of liver tissue
H Morales-Navarrete, H Nonaka, A Scholich… - Elife, 2019 - elifesciences.org
Functional tissue architecture originates by self-assembly of distinct cell types, following
tissue-specific rules of cell-cell interactions. In the liver, a structural model of the lobule was …
tissue-specific rules of cell-cell interactions. In the liver, a structural model of the lobule was …
[HTML][HTML] Anisotropic expansion of hepatocyte lumina enforced by apical bulkheads
Lumen morphogenesis results from the interplay between molecular pathways and
mechanical forces. In several organs, epithelial cells share their apical surfaces to form a …
mechanical forces. In several organs, epithelial cells share their apical surfaces to form a …
Learning developmental mode dynamics from single-cell trajectories
Embryogenesis is a multiscale process during which developmental symmetry breaking
transitions give rise to complex multicellular organisms. Recent advances in high-resolution …
transitions give rise to complex multicellular organisms. Recent advances in high-resolution …
[HTML][HTML] Resilience of three-dimensional sinusoidal networks in liver tissue
J Karschau, A Scholich, J Wise… - PLoS computational …, 2020 - journals.plos.org
Can three-dimensional, microvasculature networks still ensure blood supply if individual
links fail? We address this question in the sinusoidal network, a plexus-like microvasculature …
links fail? We address this question in the sinusoidal network, a plexus-like microvasculature …
Induction of Bile Canaliculi-Forming Hepatocytes from Human Pluripotent Stem Cells
L Matakovic, AW Overeem, K Klappe… - … : Methods and Protocols, 2022 - Springer
Cell polarity and formation of bile canaliculi can be achieved in hepatocytes which are
generated from patient-derived induced pluripotent stem cells. This allows for the study of …
generated from patient-derived induced pluripotent stem cells. This allows for the study of …
Curvature strains as a global orchestrator of morphogenesis
JB Kirkegaard - Physical Review Research, 2022 - APS
Successful morphogenesis on the scale of organs or organisms requires strict coordination
between the constituent cells whose action on the local scale must be orchestrated …
between the constituent cells whose action on the local scale must be orchestrated …
Geometry and transport in development
NF Romeo - 2023 - dspace.mit.edu
Shape changes are some of the most visually striking features of biological development at
all scales of living matter. With recent advances in high-resolution microscopy, it becomes …
all scales of living matter. With recent advances in high-resolution microscopy, it becomes …
Network permeability changes according to a quadratic power law upon removal of a single edge
S Lange, BM Friedrich - Europhysics Letters, 2021 - iopscience.iop.org
We report a phenomenological power law for the reduction of network permeability in
statistically homogeneous spatial networks upon removal of a single edge. We characterize …
statistically homogeneous spatial networks upon removal of a single edge. We characterize …
Correction: Quantification of nematic cell polarity in three-dimensional tissues
A Scholich, S Syga, H Morales-Navarrete… - PLoS Computational …, 2021 - journals.plos.org
Correction: Quantification of nematic cell polarity in three-dimensional tissues Page 1 CORRECTION
Correction: Quantification of nematic cell polarity in three-dimensional tissues André Scholich …
Correction: Quantification of nematic cell polarity in three-dimensional tissues André Scholich …