Pleiotropic AT1 Receptor Signaling Pathways Mediating Physiological and Pathogenic Actions of Angiotensin II
L Hunyady, KJ Catt - Molecular endocrinology, 2006 - academic.oup.com
Abstract Angiotensin II (Ang II) activates a wide spectrum of signaling responses via the AT1
receptor (AT1R) that mediate its physiological control of blood pressure, thirst, and sodium …
receptor (AT1R) that mediate its physiological control of blood pressure, thirst, and sodium …
International Union of Basic and Clinical Pharmacology. XCIX. Angiotensin receptors: interpreters of pathophysiological angiotensinergic stimuli
SS Karnik, H Unal, JR Kemp, KC Tirupula… - Pharmacological …, 2015 - ASPET
The renin angiotensin system (RAS) produced hormone peptides regulate many vital body
functions. Dysfunctional signaling by receptors for RAS peptides leads to pathologic states …
functions. Dysfunctional signaling by receptors for RAS peptides leads to pathologic states …
Brain renin-angiotensin—a new look at an old system
JW Wright, JW Harding - Progress in neurobiology, 2011 - Elsevier
The classic renin-angiotensin system (RAS) is described as a circulating hormone system
focused on cardiovascular and body water regulation, with angiotensin II as its major …
focused on cardiovascular and body water regulation, with angiotensin II as its major …
The brain renin–angiotensin system: a diversity of functions and implications for CNS diseases
JW Wright, JW Harding - Pflügers Archiv-European Journal of Physiology, 2013 - Springer
The classic renin–angiotensin system (RAS) was initially described as a hormone system
designed to mediate cardiovascular and body water regulation, with angiotensin II as its …
designed to mediate cardiovascular and body water regulation, with angiotensin II as its …
Angiotensin receptor subtype mediated physiologies and behaviors: new discoveries and clinical targets
JW Wright, BJ Yamamoto, JW Harding - Progress in neurobiology, 2008 - Elsevier
The renin–angiotensin system (RAS) mediates several classic physiologies including body
water and electrolyte homeostasis, blood pressure, cyclicity of reproductive hormones and …
water and electrolyte homeostasis, blood pressure, cyclicity of reproductive hormones and …
The brain angiotensin system and extracellular matrix molecules in neural plasticity, learning, and memory
JW Wright, JW Harding - Progress in neurobiology, 2004 - Elsevier
The brain renin–angiotensin system (RAS) has long been known to regulate several classic
physiologies including blood pressure, sodium and water balance, cyclicity of reproductive …
physiologies including blood pressure, sodium and water balance, cyclicity of reproductive …
The angiotensin II type 2 receptor causes constitutive growth of cardiomyocytes and does not antagonize angiotensin II type 1 receptor–mediated hypertrophy
A D'Amore, MJ Black, WG Thomas - Hypertension, 2005 - Am Heart Assoc
Angiotensin II (Ang II) has important actions on the heart via type 1 (AT1) and type 2 (AT2)
receptors. The link between AT1 receptor activation and the hypertrophy of cardiomyocytes …
receptors. The link between AT1 receptor activation and the hypertrophy of cardiomyocytes …
The brain RAS and Alzheimer's disease
JW Wright, JW Harding - Experimental neurology, 2010 - Elsevier
Alzheimer's disease (AD) has become a major world-wide health problem with ever rising
costs associated with the treatment and care of afflicted individuals. As life expectancy has …
costs associated with the treatment and care of afflicted individuals. As life expectancy has …
Activation of the Mas receptor by angiotensin-(1–7) in the renin–angiotensin system mediates mesenteric vasodilatation in cirrhosis
JA Grace, S Klein, CB Herath, M Granzow… - Gastroenterology, 2013 - Elsevier
Background & Aims Splanchnic vascular hypocontractility with subsequent increased portal
venous inflow leads to portal hypertension. Although the renin− angiotensin system …
venous inflow leads to portal hypertension. Although the renin− angiotensin system …
[HTML][HTML] Acute and subchronic exposure to air particulate matter induces expression of angiotensin and bradykinin-related genes in the lungs and heart: Angiotensin-II …
OG Aztatzi-Aguilar, M Uribe-Ramírez… - Particle and fibre …, 2015 - Springer
Background Particulate matter (PM) adverse effects on health include lung and heart
damage. The renin-angiotensin-aldosterone (RAAS) and kallikrein-kinin (KKS) endocrine …
damage. The renin-angiotensin-aldosterone (RAAS) and kallikrein-kinin (KKS) endocrine …