ipso-Annulation represents an attractive approach to synthesize a variety of spirocyclic
compounds having a quaternary carbon center. Furthermore, these compounds also serve …

An electrochemical electrophilic bromination/spirocyclization of N-benzyl-acrylamides with 2-
bromoethan-1-ol as the brominating reagent has been developed. The paired electrolysis …

A mild and convenient visible-light-induced method has been developed for the construction
of 3-sulfonyl and 3-sulfenyl azaspiro [4, 5] trienones through metal-free difunctionalization of …

A visible light-mediated difluoromethylation of N-benzylacrylamides with HCF2SO2Cl as the
HCF2 radical precursor is described. The reaction incorporates a tandem cyclization …

A novel and direct oxidative spirocyclization of arylpropiolamides with sulfonylhydrazides
leading to 3-sulfonated azaspiro [4, 5] trienones has been developed under metal-free …

An electrochemical facilitated three-component trifluoromethylation/spirocyclization reaction
of N-(arylsulfonyl) acrylamides, CF3SO2Na, and H2O has been developed. Without the …

The dearomative cyclization of linear amides to complex spirocyclic butyrolactams has been
enabled by photoredox catalysis through a reductive radical–polar crossover mechanism …

A visible-light-induced cascade Meerwein addition/cyclization of alkenes involving C–F
bond cleavage was developed. This method offers a rapid access to azaspirocyclic …

Copper-catalyzed intramolecular trifluoromethylation of N-benzylacrylamides coupled with
dearomatization was achieved and used to regiospecifically construct a variety of …

Visible light-induced intramolecular dearomative cyclization of α-bromo- N -benzyl-alkylamides:
efficient construction of 2-azaspiro[4.5]decanes - Chemical Communications (RSC Publishing) …