[HTML][HTML] Oxidative stress during acetaminophen hepatotoxicity: Sources, pathophysiological role and therapeutic potential
Acetaminophen (APAP) hepatotoxicity is characterized by an extensive oxidative stress.
However, its source, pathophysiological role and possible therapeutic potential if targeted …
However, its source, pathophysiological role and possible therapeutic potential if targeted …
Pulmonary oxidative stress, inflammation and cancer: respirable particulate matter, fibrous dusts and ozone as major causes of lung carcinogenesis through reactive …
A Valavanidis, T Vlachogianni, K Fiotakis… - International journal of …, 2013 - mdpi.com
Reactive oxygen or nitrogen species (ROS, RNS) and oxidative stress in the respiratory
system increase the production of mediators of pulmonary inflammation and initiate or …
system increase the production of mediators of pulmonary inflammation and initiate or …
Microplastics effects on soil biota are dependent on their properties: a meta-analysis
Microplastics (MPs) pollution is identified as an important new global change factor
potentially influencing ecosystem functions and services. MPs have been shown to strongly …
potentially influencing ecosystem functions and services. MPs have been shown to strongly …
Myeloid cell-derived reactive oxygen species induce epithelial mutagenesis
Ö Canli, AM Nicolas, J Gupta, F Finkelmeier… - Cancer cell, 2017 - cell.com
Increased oxidative stress has been suggested to initiate and promote tumorigenesis by
inducing DNA damage and to suppress tumor development by triggering apoptosis and …
inducing DNA damage and to suppress tumor development by triggering apoptosis and …
Advances in metal-induced oxidative stress and human disease
Detailed studies in the past two decades have shown that redox active metals like iron (Fe),
copper (Cu), chromium (Cr), cobalt (Co) and other metals undergo redox cycling reactions …
copper (Cu), chromium (Cr), cobalt (Co) and other metals undergo redox cycling reactions …
Oxidative stress and pathophysiology of ischemic stroke: novel therapeutic opportunities
R Rodrigo, R Fernandez-Gajardo… - CNS & Neurological …, 2013 - ingentaconnect.com
Stroke is the second leading cause of death, after ischemic heart disease, and accounts for
9% of deaths worldwide. According to the World Health Organization [WHO], 15 million …
9% of deaths worldwide. According to the World Health Organization [WHO], 15 million …
Role of oxidative stress in the pathogenesis of nonalcoholic steatohepatitis
The worldwide rising prevalence of obesity and insulin resistance is associated with a
parallel increase in nonalcoholic fatty liver disease (NAFLD). NAFLD is characterized by …
parallel increase in nonalcoholic fatty liver disease (NAFLD). NAFLD is characterized by …
High levels of NRF2 sensitize temozolomide-resistant glioblastoma cells to ferroptosis via ABCC1/MRP1 upregulation
I De Souza, LKS Monteiro, CB Guedes, MM Silva… - Cell Death & …, 2022 - nature.com
Glioblastoma patients have a poor prognosis mainly due to temozolomide (TMZ) resistance.
NRF2 is an important transcript factor involved in chemotherapy resistance due to its …
NRF2 is an important transcript factor involved in chemotherapy resistance due to its …
Molecular targets of oxidative stress
SV Avery - Biochemical Journal, 2011 - portlandpress.com
Aerobic life requires organisms to resist the damaging effects of ROS (reactive oxygen
species), particularly during stress. Extensive research has established a detailed picture of …
species), particularly during stress. Extensive research has established a detailed picture of …
Mangifera indica (Mango): A Promising Medicinal Plant for Breast Cancer Therapy and Understanding Its Potential Mechanisms of Action
Globally, breast cancer is the most common cancer type and is one of the most significant
causes of deaths in women. To date, multiple clinical interventions have been applied …
causes of deaths in women. To date, multiple clinical interventions have been applied …