LeuO is a global regulator of gene expression in Salmonella enterica serovar Typhimurium

SC Dillon, E Espinosa, K Hokamp… - Molecular …, 2012 - Wiley Online Library
We report the first investigation of the binding of the Salmonella enterica LeuO LysR‐type
transcription regulator to its genomic targets in vivo. Chromatin‐immunoprecipitation‐on …

The Subtleties and Contrasts of the LeuO Regulator in Salmonella Typhi: Implications in the Immune Response

C Guadarrama, T Villaseñor, E Calva - Frontiers in Immunology, 2014 - frontiersin.org
Salmonella are facultative intracellular pathogens. Salmonella infection occurs mainly by
expression of two Salmonella pathogenicity Islands (SPI-1 and SPI-2). SPI-1 encodes …

The Salmonella enterica serovar Typhi ltrRompRompCompF genes are involved in resistance to the bile salt sodium deoxycholate and in bacterial …

JM Villarreal, N Becerra‐Lobato… - Molecular …, 2014 - Wiley Online Library
A characterization of the LtrR regulator, an S. T yphi protein belonging to the LysR family is
presented. Proteomics, outer membrane protein profiles and transcriptional analyses …

Regulation of Salmonella enterica pathogenicity island 1 (SPI‐1) by the LysR‐type regulator LeuO

E Espinosa, J Casadesús - Molecular microbiology, 2014 - Wiley Online Library
LeuO is a quiescent LysR‐type regulator belonging to the H‐NS regulon. Activation of leuO
transcription represses expression of pathogenicity island 1 (SPI‐1) in S almonella enterica …

The Salmonella enterica serovar Typhi LeuO global regulator forms tetramers: residues involved in oligomerization, DNA binding, and transcriptional regulation

C Guadarrama, A Medrano-López… - Journal of …, 2014 - Am Soc Microbiol
LeuO is a LysR-type transcriptional regulator (LTTR) that has been described to be a global
regulator in Escherichia coli and Salmonella enterica, since it positively and negatively …

The human bile salt sodium deoxycholate induces metabolic and cell envelope changes in Salmonella Typhi leading to bile resistance

IB Olivar-Casique… - Journal of Medical …, 2022 - microbiologyresearch.org
Introduction. Salmonella enterica serovar Typhi (S. Typhi) is the etiological agent of typhoid
fever. To establish an infection in the human host, this pathogen must survive the presence …

The coming of age of the LeuO regulator

I Hernández‐Lucas, E Calva - Molecular microbiology, 2012 - Wiley Online Library
LeuO is a quiescent genetic regulator present in many bacteria, which forms part of the H‐
NS regulon. LeuO in turn has been proposed to activate a subset of genes of the regulon by …

Additional regulatory activities of MrkH for the transcriptional expression of the Klebsiella pneumoniae mrk genes: Antagonist of H-NS and repressor

MA Ares, JL Fernández-Vázquez, S Pacheco… - PLoS …, 2017 - journals.plos.org
Klebsiella pneumoniae is a common opportunistic pathogen causing nosocomial infections.
One of the main virulence determinants of K. pneumoniae is the type 3 pilus (T3P). T3P …

CRISPR-Cas system presents multiple transcriptional units including antisense RNAs that are expressed in minimal medium and upregulated by pH in Salmonella …

L Medina-Aparicio, JE Rebollar-Flores… - …, 2017 - microbiologyresearch.org
The CRISPR-Cas system is involved in bacterial immunity, virulence, gene regulation,
biofilm formation and sporulation. In Salmonella enterica serovar Typhi, this system consists …

Stationary‐phase induction of vvpS expression by three transcription factors: repression by LeuO and activation by SmcR and CRP

JA Kim, JH Park, MA Lee, HJ Lee, SJ Park… - Molecular …, 2015 - Wiley Online Library
An exoprotease of V ibrio vulnificus, VvpS, exhibits an autolytic function during the stationary
phase. To understand how vvpS expression is controlled, the regulators involved in vvpS …