Tissue damage from neutrophil-induced oxidative stress in COVID-19

M Laforge, C Elbim, C Frère, M Hémadi… - Nature Reviews …, 2020 - nature.com
The high neutrophil to lymphocyte ratio observed in critically ill patients with COVID-19 is
associated with excessive levels of reactive oxygen species (ROS), which promote a …

Redox imbalance links COVID-19 and myalgic encephalomyelitis/chronic fatigue syndrome

BD Paul, MD Lemle, AL Komaroff… - Proceedings of the …, 2021 - National Acad Sciences
Although most patients recover from acute COVID-19, some experience postacute sequelae
of severe acute respiratory syndrome coronavirus 2 infection (PASC). One subgroup of …

[HTML][HTML] Neutrophils and COVID-19: The road so far

LHA Cavalcante-Silva, DCM Carvalho… - International …, 2021 - Elsevier
The SARS-Cov2 infection triggers a multisystem inflammatory disorder, knowing as COVID-
19, a pandemic disease. This disease is characterized by acute respiratory distress …

Cutaneous manifestations of COVID-19: a systematic review

H Singh, H Kaur, K Singh, CK Sen - Advances in wound care, 2021 - liebertpub.com
Objective: Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), is currently a pandemic. Although pulmonary health …

[HTML][HTML] Understanding the role of neutrophils in acute respiratory distress syndrome

SC Yang, YF Tsai, YL Pan, TL Hwang - Biomedical Journal, 2021 - Elsevier
Acute respiratory distress syndrome (ARDS) is difficult to treat and is associated with a high
mortality rate. The most severe form of coronavirus disease 2019 (COVID-19) also leads to …

Aging & COVID-19 susceptibility, disease severity, and clinical outcomes: The role of entangled risk factors

M Farshbafnadi, SK Zonouzi, M Sabahi… - Experimental …, 2021 - Elsevier
Abstract The emergence of Severe Acute Respiratory Syndrome Corona Virus 2 (SARS-CoV-
2) in late 2019 has been associated with a high rate of mortality and morbidity. It has been …

[PDF][PDF] The vascular perspective on acute and chronic lung disease

I Borek, A Birnhuber, NF Voelkel… - Journal of Clinical …, 2023 - Am Soc Clin Investig
The pulmonary vasculature has been frequently overlooked in acute and chronic lung
diseases, such as acute respiratory distress syndrome (ARDS), pulmonary fibrosis (PF), and …

Mitochondrial DNA and TLR9 activation contribute to SARS-CoV-2-induced endothelial cell damage

TJ Costa, SR Potje, TFC Fraga-Silva… - Vascular …, 2022 - Elsevier
Background and purpose Mitochondria play a central role in the host response to viral
infection and immunity, being key to antiviral signaling and exacerbating inflammatory …

[HTML][HTML] The role of NADPH oxidases in infectious and inflammatory diseases

JP Taylor, MT Hubert - Redox biology, 2021 - Elsevier
Nicotinamide adenine dinucleotide phosphate (NADPH) oxidases (NOX) are enzymes that
generate superoxide or hydrogen peroxide from molecular oxygen utilizing NADPH as an …

[HTML][HTML] Therapeutic potential of ginger against COVID-19: Is there enough evidence?

A Jafarzadeh, S Jafarzadeh, M Nemati - Journal of Traditional Chinese …, 2021 - Elsevier
In addition to the respiratory system, severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) strikes other systems, including the digestive, circulatory, urogenital, and …