Tissue-engineered decellularized extracellular matrix (ECM) scaffolds hold great potential to
address the donor shortage as well as immunologic rejection attributed to cells in …

The use of bioprostheses for heart valve therapy has gradually evolved over several
decades and both surgical and transcatheter devices are now highly successful. The rapid …

Bioprosthetic heart valves (BHVs) are commonly used to replace severely diseased heart
valves but their susceptibility to structural valve degeneration (SVD) limits their use in young …

Cancer immunotherapy aims to harness the immune system to combat malignant processes.
Transformed cells harbor diverse modifications that lead to formation of neoantigens …

Despite early realization of the need to control inherent immunogenicity of bioprosthetic
replacement heart valves and thereby mitigate the ensuing host response and its associated …

Aims Bioprosthetic aortic valve degeneration demonstrates pathological similarities to aortic
stenosis. Lipoprotein (a)[Lp (a)] is a well-recognized risk factor for incident aortic stenosis …

Bioprosthetic materials based on mammalian pericardium tissue are the gold standard in
reconstructive surgery. Their application range covers repair of rectovaginal septum defects …

Glutaraldehyde (GA)-treated bovine pericardium is still the gold standard for the fabrication
of bioprostheses needed for the surgical treatment of valvular malfunction. Although …

Background The present population‐based cohort study investigated long‐term mortality
after surgical aortic valve replacement (AVR) with bioprosthetic (B) or mechanical aortic …

Bioprosthetic leaflets made from animal tissues are used in the majority of surgical and
transcatheter cardiac valve replacements. This study develops a new surgical bioprosthesis …