POC SCTs are not able to characterise the complexity of trauma-associated coagulopathy.
VETs provide a rapid estimation of underlying haemostatic disorders, thereby providing …

Anticoagulant drugs (ie, unfractionated heparin, low-molecular-weight heparins, vitamin K
antagonists, and direct oral anticoagulants) are widely employed in preventing and treating …

Importance Critical bleeding is associated with a high mortality rate in patients with trauma.
Hemorrhage is exacerbated by a complex derangement of coagulation, including an acute …

The fibrinolytic system is a key player in keeping the haemostatic balance, and changes in
fibrinolytic capacity can lead to both bleeding-related and thrombosis-related disorders. Our …

Background Trauma-induced coagulopathy (TIC) is common in trauma patients with major
hemorrhage. Prothrombin complex concentrate (PCC) is used as a potential treatment for …

This is a narrative review of the published evidence for bleeding management in critically ill
patients in different clinical settings in the intensive care unit (ICU). We aimed to describe …

The biggest obstacle to treating wound healing continues to be the production of simple,
inexpensive wound dressings that satisfy the demands associated with full process of repair …

Massive trauma remains a leading cause of death and a global public health burden. Post-
traumatic coagulopathy may be present even before the onset of resuscitation, and …

Although abundant data confirm the efficacy and safety profile of the developed vaccines
against COVID-19, there are still some concerns regarding vaccination in high-risk …

Haemorrhagic shock is frequent in critical care settings and responsible for a high mortality
rate due to multiple organ dysfunction and coagulopathy. The management of critically ill …