Consensus and update on the definition of on-treatment platelet reactivity to adenosine diphosphate associated with ischemia and bleeding

US Tantry, L Bonello, D Aradi, MJ Price… - Journal of the American …, 2013 - jacc.org
Dual antiplatelet therapy with aspirin and a P2Y12 receptor blocker is a key strategy to
reduce platelet reactivity and to prevent thrombotic events in patients treated with …

Pharmacology of antithrombotic drugs: an assessment of oral antiplatelet and anticoagulant treatments

JL Mega, T Simon - The Lancet, 2015 - thelancet.com
Antithrombotic drugs, which include antiplatelet and anticoagulant therapies, prevent and
treat many cardiovascular disorders and, as such, are some of the most commonly …

[HTML][HTML] Antiplatelet therapy after percutaneous coronary intervention

DJ Angiolillo, M Galli, JP Collet, A Kastrati… - …, 2022 - ncbi.nlm.nih.gov
Antiplatelet therapy is key to reducing local thrombotic complications and systemic
ischaemic events among patients undergoing percutaneous coronary interventions (PCI) …

[PDF][PDF] 2015 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation

M Roffi, C Patrono, JP Collet, C Mueller… - Polish Heart …, 2015 - journals.viamedica.pl
5. Leczenie.............................................................. 1225 5.1. Farmakoterapia
niedokrwienia...................... 1225 5.1. 1. Ogólne leczenie objawowe................. 1225 5.1. 2 …

[PDF][PDF] 2014 ESC/EACTS Guidelines on myocardial revascularization

S Windecker, P Kolh, F Alfonso… - Kardiologia Polska …, 2014 - journals.viamedica.pl
Zachęca się pracowników opieki zdrowotnej, aby w pełni uwzględniali te wytyczne
ESC/EACTS, gdy dokonują oceny klinicznej, a także kiedy określają i realizują medyczne …

Platelet reactivity and clinical outcomes after coronary artery implantation of drug-eluting stents (ADAPT-DES): a prospective multicentre registry study

GW Stone, B Witzenbichler, G Weisz, MJ Rinaldi… - The Lancet, 2013 - thelancet.com
Background The relation between platelet reactivity and stent thrombosis, major bleeding,
and other adverse events after coronary artery implantation of drug-eluting stents has been …

[HTML][HTML] Recommendations for the standardization of light transmission aggregometry: a consensus of the working party from the platelet physiology subcommittee of …

M Cattaneo, C Cerletti, P Harrison… - Journal of Thrombosis …, 2013 - Elsevier
Light transmission aggregometry (LTA), which was independently developed in 1962 by
Born 1 and O'Brien 2, is considered the gold standard for testing platelet function, because it …

t-tests, non-parametric tests, and large studies—a paradox of statistical practice?

MW Fagerland - BMC medical research methodology, 2012 - Springer
Background During the last 30 years, the median sample size of research studies published
in high-impact medical journals has increased manyfold, while the use of non-parametric …

Expert position paper on the role of platelet function testing in patients undergoing percutaneous coronary intervention

D Aradi, RF Storey, A Komócsi, D Trenk… - European heart …, 2014 - academic.oup.com
Optimizing outcomes after percutaneous coronary intervention (PCI) requires balancing
between the risks of thrombotic and bleeding events in individual patients. 1–3 However …

Point-of-care genetic testing for personalisation of antiplatelet treatment (RAPID GENE): a prospective, randomised, proof-of-concept trial

JD Roberts, GA Wells, MR Le May, M Labinaz… - The Lancet, 2012 - thelancet.com
Background Prospective assessment of pharmacogenetic strategies has been limited by an
inability to undertake bedside genetic testing. The CYP2C19* 2 allele is a common genetic …