Hesperidin protects liver and kidney against sodium fluoride-induced toxicity through anti-apoptotic and anti-autophagic mechanisms

C Caglayan, FM Kandemir, E Darendelioğlu… - Life Sciences, 2021 - Elsevier
Aim High dose of fluoride intake is associated with toxic effects on liver and kidney tissues.
One approach to tackle these toxicities is using natural antioxidants as supplements. This …

Hesperidin mitigates cyclophosphamide-induced testicular dysfunction via altering the hypothalamic pituitary gonadal axis and testicular steroidogenesis …

T Khamis, AA Hegazy, SSA El-Fatah, ER Abdelfattah… - Pharmaceuticals, 2023 - mdpi.com
Cyclophosphamide (CP) is a cytotoxic, cell cycle, non-specific, and antiproliferative drug.
This study aimed to address the toxic effects of CP on male fertility and the possible …

[HTML][HTML] Moringa oleifera ethanolic extract attenuates tilmicosin-induced renal damage in male rats via suppression of oxidative stress, inflammatory injury, and …

SM Abou-Zeid, AI Ahmed, A Awad… - Biomedicine & …, 2021 - Elsevier
Tilmicosin (Til) is a popular macrolide antibiotic, widely used in veterinary practice. The
present study was designed to address the efficacy of Moringa oleifera ethanolic extract …

Ameliorative effect of traditional polyherbal formulation on TNF-α, IL-1β and Caspase-3 expression in kidneys of wistar rats against sodium fluoride induced oxidative …

MU Khan, P Basist, S Zahiruddin, NR Penumallu… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Sharbat-e-bazoori Motadil (SBM) is a polyherbal
formulation that have been used for centuries as a part of the Unani system of medicine for …

Moderate exercise relieves fluoride-induced liver and kidney inflammatory responses through the IKKβ/NFκB pathway

Y Yu, R Niu, F Zhao, Y Zhao, J Wang, J Wang… - … Science and Pollution …, 2022 - Springer
With the intensification of environmental pollution, the content of fluoride is increasing in
human and animal living environments. Long-term fluoride exposure can cause damage to …

Alhagi maurorum Ethanolic Extract Rescues Hepato-Neurotoxicity and Neurobehavioral Alterations Induced by Lead in Rats via Abrogating Oxidative Stress and the …

TM Saber, AMA Abo-Elmaaty, EN Said, RR Beheiry… - Antioxidants, 2022 - mdpi.com
This work investigated the probable protective effect of an Alhagi maurorum ethanolic extract
on the hepatotoxicity and neurotoxicity accompanied by neurobehavioral deficits caused by …

Effects of a Short-Term Lipopolysaccharides Challenge on Mouse Brain and Liver Peroxisomal Antioxidant and β-Oxidative Functions: Protective Action of Argan Oil

S Essadek, H Bouchab, R El Kebbaj, C Gondcaille… - Pharmaceuticals, 2022 - mdpi.com
During sepsis, the imbalance between oxidative insult and body antioxidant response
causes the dysfunction of organs, including the brain and liver. Exposing mice to bacterial …

The antioxidant, anti-apoptotic, and proliferative potency of argan oil against betamethasone-induced oxidative renal damage in rats

SH Orabi, TS Allam, SM Shawky, EAE Tahoun… - Biology, 2020 - mdpi.com
Simple Summary The present study aimed to investigate the protective effect of argan oil
against nephrotoxic effect following overdose and long-term administration of …

Fermented Rooibos tea (Aspalathus linearis) Ameliorates Sodium Fluoride-Induced Cardiorenal Toxicity, Oxidative Stress, and Inflammation via Modulation of NF-κB …

OR Ajuwon, TA Adeleke, BO Ajiboye, AO Lawal… - Cardiovascular …, 2024 - Springer
High dose of fluoride intake is associated with toxic effects on kidney and cardiac tissues.
This study evaluated the potential protective effect of fermented rooibos tea (RTE) on sodium …

Evaluation of toxicity, nephroprotective and hepatoprotective activities of Argan oil on CCl4-induced nephrotoxicity and hepatotoxicity in Wistar rats

B Mohamed, M Samira, M Mohamed… - Arabian Journal of …, 2021 - revues.imist.ma
In traditional therapy, Argania spinosa L. seeds oil used as a nephroprotective and
hepatoprotective agent. The present work aims to investigate the acute toxicity of unroasted …