Melatonin as a hormone: new physiological and clinical insights

J Cipolla-Neto, FG Amaral - Endocrine reviews, 2018 - academic.oup.com
Melatonin is a ubiquitous molecule present in almost every live being from bacteria to
humans. In vertebrates, besides being produced in peripheral tissues and acting as an …

Extrapineal melatonin: sources, regulation, and potential functions

D Acuña-Castroviejo, G Escames, C Venegas… - Cellular and molecular …, 2014 - Springer
Endogenous melatonin is synthesized from tryptophan via 5-hydroxytryptamine. It is
considered an indoleamine from a biochemical point of view because the melatonin …

Melatonin and pregnancy in the human

H Tamura, Y Nakamura, MP Terron, LJ Flores… - Reproductive …, 2008 - Elsevier
The purpose of this systematic review is to access the current state of knowledge concerning
the role for melatonin in human pregnancy. Melatonin is a neuroendocrine hormone …

Oxidative stress of the newborn in the pre‐and postnatal period and the clinical utility of melatonin

E Gitto, S Pellegrino, P Gitto, I Barberi… - Journal of pineal …, 2009 - Wiley Online Library
Newborns, and especially those delivered preterm, are probably more prone to oxidative
stress than individuals later in life. Also during pregnancy, increased oxygen demand …

Maternal‐fetal transfer of melatonin in pregnant women near term

Y Okatani, K Okamoto, K Hayashi… - Journal of pineal …, 1998 - Wiley Online Library
Our objective was to evaluate the maternal‐fetal transfer of melatonin in pregnant women.
Serum melatonin concentration was measured by high‐performance liquid chromatography …

Utility of high doses of melatonin as adjunctive anticonvulsant therapy in a child with severe myoclonic epilepsy: two years' experience

A Molina‐Carballo, A Muñoz‐Hoyos… - Journal of pineal …, 1997 - Wiley Online Library
Molina‐Carballo A, Muñoz‐Hoyos A, Reiter RJ, Sánchez‐Forte M, Moreno‐Madrid F, Rufo‐
Campos M, Molina‐Font JA, Acuña‐Castroviejo D. Utility of high doses of melatonin as …

Melatonin and human reproduction: shedding light on the darkness hormone

V Srinivasan, WD Spence… - Gynecological …, 2009 - Taylor & Francis
Melatonin, N-acetyl-5-methoxytryptamine, is a molecule with diverse physiological functions.
This neuro-hormone affects reproductive performance in a wide variety of species. In most …

Update on the use of melatonin in pediatrics

E Gitto, S Aversa, RJ Reiter, I Barberi… - Journal of pineal …, 2011 - Wiley Online Library
Melatonin, an endogenously produced indoleamine, is a highly effective antioxidant, free
radical scavenger, and a primary circadian regulator. Melatonin has important antioxidant …

Potential utility of melatonin as an antioxidant during pregnancy and in the perinatal period

S Aversa, S Pellegrino, I Barberi… - The Journal of …, 2012 - Taylor & Francis
Reactive oxygen species (ROS) play a critical role in the pathogenesis of various diseases
during pregnancy and the perinatal period. Newborns are more prone to oxidative stress …

Hypothermia plus melatonin in asphyctic newborns: a randomized-controlled pilot study

A Jerez-Calero, MT Salvatierra-Cuenca… - Pediatric Critical Care …, 2020 - journals.lww.com
Objectives: To investigate the effect of adding melatonin to hypothermia treatment on
neurodevelopmental outcomes in asphyctic newborns. Design: Pilot multicenter …